Aristeromycin
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| Category | Antibiotics |
| Catalog number | BBF-00561 |
| CAS | 19186-33-5 |
| Molecular Weight | 265.27 |
| Molecular Formula | C11H15N5O3 |
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Description
Aristeromycin is a nucleoside antibiotic produced by Streptomyces citricolor. It has a minimum inhibitory concentration of 5 mg/mL against Xanthomonas oryzae and Pear.
Specification
| Synonyms | Cycloadenosine; (1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol |
| IUPAC Name | (1R,2S,3R,5R)-3-(6-aminopurin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol |
| Canonical SMILES | C1C(C(C(C1N2C=NC3=C(N=CN=C32)N)O)O)CO |
| InChI | InChI=1S/C11H15N5O3/c12-10-7-11(14-3-13-10)16(4-15-7)6-1-5(2-17)8(18)9(6)19/h3-6,8-9,17-19H,1-2H2,(H2,12,13,14)/t5-,6-,8-,9+/m1/s1 |
| InChI Key | UGRNVLGKAGREKS-GCXDCGAKSA-N |
Properties
| Appearance | Colorless Prismatic Crystal |
| Antibiotic Activity Spectrum | fungi |
| Boiling Point | 595.1°C at 760 mmHg |
| Melting Point | 213-215°C (dec.) |
| Density | 1.92 g/cm3 |
| Solubility | Soluble in Acetic acid, Water, Methanol |
Reference Reading
1.The 5'-nor aristeromycin analogues of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-thiophenyladenosine.
Das SR1, Schneller SW. Nucleosides Nucleotides Nucleic Acids. 2014;33(10):668-77. doi: 10.1080/15257770.2014.917671.
To extend the potential of 5'-noraristeromycin (and its enantiomer) as potential antiviral candidates, the enantiomers of the carbocyclic 5'-nor derivatives of 5'-methylthio-5'-deoxyadenosine and 5'-phenylthio-5'-deoxyadenosine have been synthesized and evaluated. None of the compounds showed meaningful antiviral activity.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
