Axenomycin B

Axenomycin B

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category Antibiotics
Catalog number BBF-00235
CAS
Molecular Weight 546.60
Molecular Formula C29H38O10

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Description

Axenomycin B is produced by the strain of Streptomyces lisandri F. I. 2604. It has antifungal, nematode and trichomonas activities.

Properties

Appearance Yellow and White Amorphous Powder
Antibiotic Activity Spectrum fungi; parasites
Melting Point 122-140 °C

Reference Reading

1. Axenomycins, new cestocidal antibiotics
C Della Bruna, M L Ricciardi, A Sanfilippo Antimicrob Agents Chemother. 1973 Jun;3(6):708-10. doi: 10.1128/AAC.3.6.708.
Axenomycins are a new group of macrolide antibiotics isolated from the fermentation broth of Streptomyces lisandri n.sp. They exhibit anthelmintic activity against tapeworms (Cestoda). Three different fractions, A, B, and D, have been obtained, the most active fraction being axenomycin D. The activities of the axenomycin complex and axenomycin D against Hymenolepis nana in mice, Taenia pisiformis, Dipylidium caninum, and Diphyllobothrium sp. in dogs, and Moniezia expansa, M. benedeni, and Avitellina centripunctata in lambs were studied in experimentally and naturally infected animals. Axenomycins were effective and well tolerated by the oral route. Worm reduction rates after a single oral dose were 90 to 100% with 5 to 10 mg of axenomycin D/kg and 50 to 100% with 20 mg of axenomycin complex/kg.

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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