Azirinomycin

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Azirinomycin
Category Others
Catalog number BBF-00244
CAS 31772-89-1
Molecular Weight 99.09
Molecular Formula C4H5NO2

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Description

Azirinomycin is produced by the strain of Streptomyces aureus. It has anti-gram positive and negative bacterial activity.

Specification

Synonyms 3-Methyl-2H-azirine-2-carboxylic acid; 2H-AZIRINE-2-CARBOXYLIC ACID, 3-METHYL-
IUPAC Name 3-methyl-2H-azirine-2-carboxylic acid
Canonical SMILES CC1=NC1C(=O)O
InChI InChI=1S/C4H5NO2/c1-2-3(5-2)4(6)7/h3H,1H3,(H,6,7)
InChI Key NHCHAEIJXKFNRU-UHFFFAOYSA-N

Properties

Appearance Dull Yellow Oil
Antibiotic Activity Spectrum gram-positive bacterial; gram-negative bacteria

Reference Reading

1. [Asymmetric syntheses of azacycloalkanes by one-pot [1+2+n] cyclization]
Shingo Harada Yakugaku Zasshi. 2013;133(9):975-82. doi: 10.1248/yakushi.13-00157.
Enantio- and diastereoselective one-pot synthesis of three- to seven-membered cis-azaheterocycles was achieved using a triggered asymmetric conjugate addition reaction of lithium amide with an enoate, followed by C- and N-alkylation of the resulting lithium 3-aminoenolate with α, ω-dihaloalkane, which can be regarded as a [1+2+n] cyclization. The usefulness of the developed methodology was clearly demonstrated by the short-step asymmetric syntheses of azirinomycin ester, nemonapride, and kopsinine.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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