BE-10988
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Enzyme inhibitors |
Catalog number | BBF-03224 |
CAS | 135261-89-1 |
Molecular Weight | 302.31 |
Molecular Formula | C13H10N4O3S |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (µmol/L) of 0.5, 0.4, 2.0, respectively.
- Specification
- Properties
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IUPAC Name | 2-(5-amino-1-methyl-4,7-dioxoindol-3-yl)-1,3-thiazole-4-carboxamide |
Canonical SMILES | CN1C=C(C2=C1C(=O)C=C(C2=O)N)C3=NC(=CS3)C(=O)N |
InChI | InChI=1S/C13H10N4O3S/c1-17-3-5(13-16-7(4-21-13)12(15)20)9-10(17)8(18)2-6(14)11(9)19/h2-4H,14H2,1H3,(H2,15,20) |
InChI Key | ZLMULFPSOBULMS-UHFFFAOYSA-N |
Appearance | Dark Red Crystalline Powder |
Boiling Point | 687°C at 760 mmHg |
Density | 1.76 g/cm3 |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
