BE-19412A
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-03229 |
| CAS | 173774-90-8 |
| Molecular Weight | 535.93 |
| Molecular Formula | C28H22ClNO8 |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
BE-19412A is an antitumor antibiotic extracted from the culture medium of Streptomyces sp. A19412. It is toxic to mouse and human tumor cells such as P388, Ehrlich, DLD-1, PC-13, MKN-45 and Colon 26, with IC50 of 0.9-5.4 μg/mL, and can prolong the survival time of CDF1 mice with Ehrlich cancer.
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- Properties
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| Synonyms | LS-94141 |
| IUPAC Name | 20-chloro-1,17,19,21-tetrahydroxy-3-methoxy-7,24-dimethyl-6-azahexacyclo[12.12.0.02,11.04,9.016,25.018,23]hexacosa-2(11),3,7,9,16,18,20,22,24-nonaene-5,15,26-trione |
| Canonical SMILES | CC1=CC2=CC3=C(C(=C2C(=O)N1)OC)C4(C(CC3)C(=O)C5=C(C6=C(C(=C(C=C6C(=C5C4=O)C)O)Cl)O)O)O |
| InChI | InChI=1S/C28H22ClNO8/c1-9-6-12-7-11-4-5-14-22(32)19-16(10(2)13-8-15(31)21(29)24(34)18(13)23(19)33)26(35)28(14,37)20(11)25(38-3)17(12)27(36)30-9/h6-8,14,31,33-34,37H,4-5H2,1-3H3,(H,30,36) |
| InChI Key | YFSXWCSVEGSUER-UHFFFAOYSA-N |
| Appearance | Greyish-green Powder |
| Antibiotic Activity Spectrum | neoplastics (Tumor) |
| Boiling Point | 862.5±65.0°C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
