Berninamycin B

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Category Bioactive by-products
Catalog number BBF-00137
CAS
Molecular Weight 1130.11
Molecular Formula C51H51N15O14S

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Description

Berninamycin B is a peptide antibiotic produced by Streptomyces bernensis NRRL 3572.

Reference Reading

1. Berninamycins B, C, and D, minor metabolites from Streptomyces bernensis
R C Lau, K L Rinehart J Antibiot (Tokyo). 1994 Dec;47(12):1466-72. doi: 10.7164/antibiotics.47.1466.
Berninamycins B, C, and D were isolated from fermentation of Streptomyces bernensis and their structures were studied with 13C NMR and FAB mass spectrometry. Berninamycin B has a valine unit in its cyclic peptide loop instead of the beta-hydroxyvaline unit found in berninamycin A. Berninamycin D has two fewer dehydroalanine units attached to the carboxyl carbon of the pyridine ring. Based on FAB-MS results, berninamycin C is postulated to have only one dehydroalanine unit attached to the carboxyl carbon of pyridine. The biogenesis of berninamycins B, C, and D is discussed.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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