Berubicin Hydrochloride
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![Berubicin Hydrochloride](https://resource.bocsci.com/structure/293736-67-1.gif)
Category | Antineoplastic |
Catalog number | BBF-05864 |
CAS | 293736-67-1 |
Molecular Weight | 670.10 |
Molecular Formula | C34H35NO11.HCl |
Purity | ≥95% |
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Description
Berubicin hydrochloride is the hydrochloride of berubicin, which is an anthracycline derivative used as a topoisomerase II inhibitor with activity in ependymoma. Berubicin hydrochloride has potential antineoplastic activity.
Specification
Related CAS | 677017-23-1 (free base) |
Synonyms | Daunorubicin Impurity 9 hydrochloride; WP 769 hydrochloride; 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-, hydrochloride (1:1); Berubicin monohydrochloride; RTA 744; WP 744 |
Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly. |
Storage | Store at -20°C |
IUPAC Name | (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-6-methyl-5-phenylmethoxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride |
Canonical SMILES | CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)OCC6=CC=CC=C6.Cl |
InChI | InChI=1S/C34H35NO11.ClH/c1-16-33(44-15-17-7-4-3-5-8-17)20(35)11-24(45-16)46-22-13-34(42,23(37)14-36)12-19-26(22)32(41)28-27(30(19)39)29(38)18-9-6-10-21(43-2)25(18)31(28)40;/h3-10,16,20,22,24,33,36,39,41-42H,11-15,35H2,1-2H3;1H/t16-,20-,22-,24-,33+,34-;/m0./s1 |
InChI Key | GPMIHHFZKBVWAZ-LMMKTYIZSA-N |
Properties
Appearance | Solid powder |
Application | A topoisomerase II inhibitor with activity in ependymoma. |
Antibiotic Activity Spectrum | Neoplastics (Tumor) |
Solubility | Soluble in DMSO |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
![](/bio-fermen.v1/images/Molecular-Weight-Calculato-4.png)