Bestatin
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Category | Enzyme inhibitors |
Catalog number | BBF-00574 |
CAS | 58970-76-6 |
Molecular Weight | 308.37 |
Molecular Formula | C16H24N2O4 |
Purity | >98% |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-00574 | 1 g | $199 | In stock |
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Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Bestatin is a specific aminopeptidase B inhibitor produced by Streptomyces olivoreticuli. Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor used in the treatment of acute myelocytic leukemia. It exhibits potential immunomodulatory and antitumor activities.
- Specification
- Properties
- Reference Reading
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Related CAS | 65391-42-6 (hydrochloride) 223763-80-2 (trifluoroacetate) |
Synonyms | Ubenimex |
Storage | Store at -20°C |
IUPAC Name | (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid |
Canonical SMILES | CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O |
InChI | InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 |
InChI Key | VGGGPCQERPFHOB-RDBSUJKOSA-N |
Source | Streptomyces sp. |
Appearance | White crystalline powder |
Application | the treatment of acute myelocytic leukemia |
Boiling Point | 604.7°C at 760 mmHg |
Melting Point | 233-236 °C |
Flash Point | 319.5°C |
Density | 1.197 g/cm3 |
Solubility | Soluble in DMSO |
LogP | 1.62400 |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
