Bhimamycin B

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Category Antibiotics
Catalog number BBF-00143
CAS
Molecular Weight 270.24
Molecular Formula C15H10O5

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Description

Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin B has moderate activity against gram-positive and gram-negative bacteria.

Specification

IUPAC Name 1-acetyl-5-hydroxy-3-methylbenzo[f][2]benzofuran-4,9-dione
Canonical SMILES CC1=C2C(=C(O1)C(=O)C)C(=O)C3=C(C2=O)C(=CC=C3)O
InChI InChI=1S/C15H10O5/c1-6(16)15-12-10(7(2)20-15)14(19)11-8(13(12)18)4-3-5-9(11)17/h3-5,17H,1-2H3
InChI Key AKOVEXVRRMSRSS-UHFFFAOYSA-N

Properties

Appearance Brown Powder
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria

Reference Reading

1. Bhimamycin A to approximately E and bhimanone: isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial Streptomycete
Serge Fotso, Rajendra P Maskey, Iris Grün-Wollny, Klaus-Peter Schulz, Morton Munk, Hartmut Laatsch J Antibiot (Tokyo). 2003 Nov;56(11):931-41. doi: 10.7164/antibiotics.56.931.
From the ethyl acetate extract of a terrestrial Streptomycete isolate, five new quinone antibiotics, bhimamycin A (2a), B (2b), C (3c), D (5a), E (7) and the new tetralone bhimanone (8) were isolated together with the known microbial products chrysophanol (1a), aloesaponarin II (1b), 3,8-dihydroxy-1-methylanthraquinone-2-carboxylic acid (1c), adenosine, 2'-deoxyadenosine, phenylacetamide, and 2-(p-hydroxyphenyl)ethanol. The structures of these natural products were deduced from the spectral data and confirmed by comparison with related compounds from the literature and by synthesis.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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