Bhimamycin E
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| Category | Antibiotics |
| Catalog number | BBF-00146 |
| CAS | |
| Molecular Weight | 246.21 |
| Molecular Formula | C13H10O5 |
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Description
Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/699. Five components A to E are separated. Bhimamycin E selectively inhibits Staphylococcus aureus.
Specification
| IUPAC Name | 3-acetyl-5-hydroxy-2-(hydroxymethyl)naphthalene-1,4-dione |
| Canonical SMILES | CC(=O)C1=C(C(=O)C2=C(C1=O)C(=CC=C2)O)CO |
| InChI | InChI=1S/C13H10O5/c1-6(15)10-8(5-14)12(17)7-3-2-4-9(16)11(7)13(10)18/h2-4,14,16H,5H2,1H3 |
| InChI Key | PLSLMDVCBUASJN-UHFFFAOYSA-N |
Properties
| Appearance | Yellow Solid |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
Reference Reading
1. Bhimamycin A to approximately E and bhimanone: isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial Streptomycete
Serge Fotso, Rajendra P Maskey, Iris Grün-Wollny, Klaus-Peter Schulz, Morton Munk, Hartmut Laatsch J Antibiot (Tokyo). 2003 Nov;56(11):931-41. doi: 10.7164/antibiotics.56.931.
From the ethyl acetate extract of a terrestrial Streptomycete isolate, five new quinone antibiotics, bhimamycin A (2a), B (2b), C (3c), D (5a), E (7) and the new tetralone bhimanone (8) were isolated together with the known microbial products chrysophanol (1a), aloesaponarin II (1b), 3,8-dihydroxy-1-methylanthraquinone-2-carboxylic acid (1c), adenosine, 2'-deoxyadenosine, phenylacetamide, and 2-(p-hydroxyphenyl)ethanol. The structures of these natural products were deduced from the spectral data and confirmed by comparison with related compounds from the literature and by synthesis.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
