Bhimamycin E

Name: Bhimamycin E
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	Antibiotics
Catalog number	BBF-00146
CAS
Molecular Weight	246.21
Molecular Formula	C13H10O5

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2 Preparative purification labs

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Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/699. Five components A to E are separated. Bhimamycin E selectively inhibits Staphylococcus aureus.

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IUPAC Name	3-acetyl-5-hydroxy-2-(hydroxymethyl)naphthalene-1,4-dione
Canonical SMILES	CC(=O)C1=C(C(=O)C2=C(C1=O)C(=CC=C2)O)CO
InChI	InChI=1S/C13H10O5/c1-6(15)10-8(5-14)12(17)7-3-2-4-9(16)11(7)13(10)18/h2-4,14,16H,5H2,1H3
InChI Key	PLSLMDVCBUASJN-UHFFFAOYSA-N

Appearance	Yellow Solid
Antibiotic Activity Spectrum	Gram-positive bacteria

1. Bhimamycin A to approximately E and bhimanone: isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial Streptomycete

Serge Fotso, Rajendra P Maskey, Iris Grün-Wollny, Klaus-Peter Schulz, Morton Munk, Hartmut Laatsch J Antibiot (Tokyo). 2003 Nov;56(11):931-41. doi: 10.7164/antibiotics.56.931.

From the ethyl acetate extract of a terrestrial Streptomycete isolate, five new quinone antibiotics, bhimamycin A (2a), B (2b), C (3c), D (5a), E (7) and the new tetralone bhimanone (8) were isolated together with the known microbial products chrysophanol (1a), aloesaponarin II (1b), 3,8-dihydroxy-1-methylanthraquinone-2-carboxylic acid (1c), adenosine, 2'-deoxyadenosine, phenylacetamide, and 2-(p-hydroxyphenyl)ethanol. The structures of these natural products were deduced from the spectral data and confirmed by comparison with related compounds from the literature and by synthesis.

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