Butyrolactone I
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Enzyme inhibitors |
Catalog number | BBF-04270 |
CAS | 87414-49-1 |
Molecular Weight | 424.44 |
Molecular Formula | C24H24O7 |
Purity | >95% by HPLC |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
It is one of a family of three butyrolactones isolated from aspergillus fumigatus. It exhibits antitumor activity and inhibits the cell cycle at the G1/S and G2/M transitions. It is a selective inhibitor of cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5.
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- Properties
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Synonyms | Olomoucin; 4'-O-Demethylversicolactone D; (2R)-2,5-Dihydro-4-hydroxy-2-[[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxo-2-furancarboxylic Acid Methyl Ester; (+)-3''-Dimethylallyl-butyrolactone II |
Storage | Store at -20°C |
IUPAC Name | methyl (2R)-4-hydroxy-2-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate |
Canonical SMILES | CC(=CCC1=C(C=CC(=C1)CC2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C(=O)OC)O)C |
InChI | InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3/t24-/m1/s1 |
InChI Key | NGOLMNWQNHWEKU-XMMPIXPASA-N |
Source | Aspergillus sp. |
Appearance | Light Yellow Solid |
Antibiotic Activity Spectrum | Neoplastics (Tumor) |
Boiling Point | 660.1±55.0°C (Predicted) |
Melting Point | 95°C (dec.) |
Density | 1.353±0.06 g/cm3 (Predicted) |
Solubility | Soluble in Ethanol, Methanol, DMF, DMSO |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
