C-2801X

Name: C-2801X
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Antibiotics
Catalog number	BBF-02758
CAS	56083-50-2
Molecular Weight	595.57
Molecular Formula	C25H29N3O12S

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Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

C-2801X is originally isolated from Streptomyces heteromorphus. It is mainly resistant to Gram-positive bacteria and negative bacteria.

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Synonyms	C 2801X
IUPAC Name	(6R,7S)-7-[[(5R)-5-amino-5-carboxypentanoyl]amino]-3-[[(Z)-3-(3,4-dihydroxyphenyl)-2-methoxyprop-2-enoyl]oxymethyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Canonical SMILES	COC(=CC1=CC(=C(C=C1)O)O)C(=O)OCC2=C(N3C(C(C3=O)(NC(=O)CCCC(C(=O)O)N)OC)SC2)C(=O)O
InChI	InChI=1S/C25H29N3O12S/c1-38-17(9-12-6-7-15(29)16(30)8-12)22(36)40-10-13-11-41-24-25(39-2,23(37)28(24)19(13)21(34)35)27-18(31)5-3-4-14(26)20(32)33/h6-9,14,24,29-30H,3-5,10-11,26H2,1-2H3,(H,27,31)(H,32,33)(H,34,35)/b17-9-/t14-,24-,25+/m1/s1
InChI Key	NJZVVAVNQYLLCW-AATDYCFQSA-N

Appearance	White Powder
Antibiotic Activity Spectrum	Gram-positive bacteria; Gram-negative bacteria
Boiling Point	974.1±65.0°C at 760 mmHg
Density	1.6±0.1 g/cm3

1. C-2801X, a new cephamycin-type antibiotic II. Isolation and characterization

H Fukase, T Hasegawa, K Hatano, H Iwasaki, M Yoneda J Antibiot (Tokyo). 1976 Feb;29(2):113-20. doi: 10.7164/antibiotics.29.113.

Two new species of Streptomyces, S. heteromorphus and heteromorphus and S. panayensis, were found to produce a new atibiotic named C-2801X together with cephamycins A and B. The antibiotics were separated from each other by column chromatography on Amberlite XAD-2 and isolated in pure form as mono-sodium salts. C-2801X mono-sodium salt has a molecular formula C25H28N3O12SNa, and exhibits antibacterial activity against Gram-positive and Gram-negative bacteria including those insensitive to cephamycins A and B. From its physicochemical and biological properties, C2801X was considered to be a new cephamycin-type antibiotic.

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