Caldariomycin
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Category | Antibiotics |
Catalog number | BBF-00203 |
CAS | 465-61-2 |
Molecular Weight | 171.02 |
Molecular Formula | C5H8Cl2O2 |
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Description
Caldariomycin is an alicyclic antibiotic produced by Caldariomyces fumago. Anti-Gram-positive bacteria.
Specification
IUPAC Name | (1S,3S)-2,2-dichlorocyclopentane-1,3-diol |
Canonical SMILES | C1CC(C(C1O)(Cl)Cl)O |
InChI | InChI=1S/C5H8Cl2O2/c6-5(7)3(8)1-2-4(5)9/h3-4,8-9H,1-2H2/t3-,4-/m0/s1 |
InChI Key | CXQAMTQEGSVLDJ-IMJSIDKUSA-N |
Properties
Appearance | Colorless needle Crystal |
Antibiotic Activity Spectrum | Gram-positive bacteria |
Solubility | Soluble in Methanol, Water |
Reference Reading
1. Isolation of the bromo analogue of caldariomycin from Caldariomyces fumago
E L Patterson, W W Andres, L A Mitscher Appl Microbiol. 1967 May;15(3):528-30. doi: 10.1128/am.15.3.528-530.1967.
When bromide ion was substituted for chloride in the growth medium of Caldariomyces fumago, a new substance was produced. It was isolated by solvent extraction and purified by alumina chromatography. Examination of the physicochemical properties of the substance led to its identification as the bromo analogue of the normal metabolite, caldariomycin. Thus, biological substitution of bromine for chlorine has been demonstrated in the metabolic formation of a purely aliphatic secondary mold metabolite.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳