Carbazomycinal

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Carbazomycinal
Category Others
Catalog number BBF-00484
CAS 103744-20-3
Molecular Weight 255.27
Molecular Formula C15H13NO3

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Description

It is produced by the strain of Streptoverticillum sp. KCC U-0166. It can inhibit the formation of aerial hyphae.

Specification

Synonyms Carbazomycin E; SCHEMBL16432825; 9H-Carbazole-1-carboxaldehyde,4-hydroxy-3-methoxy-2-methyl
IUPAC Name 4-hydroxy-3-methoxy-2-methyl-9H-carbazole-1-carbaldehyde
Canonical SMILES CC1=C(C2=C(C3=CC=CC=C3N2)C(=C1OC)O)C=O
InChI InChI=1S/C15H13NO3/c1-8-10(7-17)13-12(14(18)15(8)19-2)9-5-3-4-6-11(9)16-13/h3-7,16,18H,1-2H3
InChI Key BEJNHSBULWLOJS-UHFFFAOYSA-N

Properties

Appearance Light Yellow Crystal
Boiling Point 512.6 °C at 760 mmHg
Melting Point 224 °C
Density 1.369 g/cm3
Solubility Soluble in Methanol

Reference Reading

1. Carbazomycins C, D, E and F, minor components of the carbazomycin complex
T Naid, T Kitahara, M Kaneda, S Nakamura J Antibiot (Tokyo). 1987 Feb;40(2):157-64. doi: 10.7164/antibiotics.40.157.
Carbazomycins C (III), D (IV), E (V) and F (VI), the minor components of the carbazomycin complex, were isolated from the cultured broth of Streptoverticillium ehimense together with carbazomycins A (II) and B (I). Among them, III and IV were shown to be new substances and their structures were elucidated as 4-hydroxy-3,6-dimethoxy-1,2-dimethylcarbazole and 3,4,6-trimethoxy-12-dimethylcarbazole, respectively, by spectroscopic and chemical means. The other components, V and VI, were found to contain an aldehyde function and were identified as carbazomycinal and 6-methoxycarbazomycinal, respectively. The antimicrobial activity of III and IV are also reported.

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