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CB-25-I

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Category Antibiotics
Catalog number BBF-02760
CAS
Molecular Weight 316.31
Molecular Formula C12H20N4O6

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Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

CB-25-I, a water-soluble dipeptide, is produced by the strain of Serratia plymuthica. It has an inhibitory effect on individual Candida bacteria (Condida albicans M-9, C. guilliermondii IFO 0454).

  • Specification
  • Properties
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Synonyms N-(R,R)-3-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine; Nbeta-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine
IUPAC Name (2S)-2-[[(2S)-2-azaniumyl-3-[[(2R,3R)-3-carbamoyloxirane-2-carbonyl]amino]propanoyl]amino]-3-methylbutanoate
Canonical SMILES CC(C)C(C(=O)[O-])NC(=O)C(CNC(=O)C1C(O1)C(=O)N)[NH3+]
InChI InChI=1S/C12H20N4O6/c1-4(2)6(12(20)21)16-10(18)5(13)3-15-11(19)8-7(22-8)9(14)17/h4-8H,3,13H2,1-2H3,(H2,14,17)(H,15,19)(H,16,18)(H,20,21)/t5-,6-,7+,8+/m0/s1
InChI Key HCGFOSJNUODEOH-RULNZFCNSA-N
Appearance Colorless Amorphous Powder
Antibiotic Activity Spectrum fungi
Boiling Point 597.2±60.0°C at 760 mmHg
Density 1.7±0.1 g/cm3
Solubility Soluble in Water
1. Isolation of CB-25-I, an antifungal antibiotic, from Serratia plymuthica
J Shoji, H Hinoo, R Sakazaki, T Kato, T Hattori, K Matsumoto, K Tawara, J Kikuchi, Y Terui J Antibiot (Tokyo). 1989 Jun;42(6):869-74. doi: 10.7164/antibiotics.42.869.
A new antifungal antibiotic, CB-25-I, was isolated from the culture broth of a strain of Serratia plymuthica. The antibiotic, a water-soluble dipeptide, is structurally related to Sch 37137 and A 19009, both produced by strains of Actinomycetales. The antibiotic exhibits inhibitory activity against Candida albicans in YNB medium (a synthetic medium), but the activity is significantly reduced in Sabouroud dextrose medium.

Bio Calculators

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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