CB-25-I
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| Category | Antibiotics |
| Catalog number | BBF-02760 |
| CAS | |
| Molecular Weight | 316.31 |
| Molecular Formula | C12H20N4O6 |
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Description
CB-25-I, a water-soluble dipeptide, is produced by the strain of Serratia plymuthica. It has an inhibitory effect on individual Candida bacteria (Condida albicans M-9, C. guilliermondii IFO 0454).
Specification
| Synonyms | N-(R,R)-3-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine; Nbeta-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine |
| IUPAC Name | (2S)-2-[[(2S)-2-azaniumyl-3-[[(2R,3R)-3-carbamoyloxirane-2-carbonyl]amino]propanoyl]amino]-3-methylbutanoate |
| Canonical SMILES | CC(C)C(C(=O)[O-])NC(=O)C(CNC(=O)C1C(O1)C(=O)N)[NH3+] |
| InChI | InChI=1S/C12H20N4O6/c1-4(2)6(12(20)21)16-10(18)5(13)3-15-11(19)8-7(22-8)9(14)17/h4-8H,3,13H2,1-2H3,(H2,14,17)(H,15,19)(H,16,18)(H,20,21)/t5-,6-,7+,8+/m0/s1 |
| InChI Key | HCGFOSJNUODEOH-RULNZFCNSA-N |
Properties
| Appearance | Colorless Amorphous Powder |
| Antibiotic Activity Spectrum | fungi |
| Boiling Point | 597.2±60.0°C at 760 mmHg |
| Density | 1.7±0.1 g/cm3 |
| Solubility | Soluble in Water |
Reference Reading
1. Isolation of CB-25-I, an antifungal antibiotic, from Serratia plymuthica
J Shoji, H Hinoo, R Sakazaki, T Kato, T Hattori, K Matsumoto, K Tawara, J Kikuchi, Y Terui J Antibiot (Tokyo). 1989 Jun;42(6):869-74. doi: 10.7164/antibiotics.42.869.
A new antifungal antibiotic, CB-25-I, was isolated from the culture broth of a strain of Serratia plymuthica. The antibiotic, a water-soluble dipeptide, is structurally related to Sch 37137 and A 19009, both produced by strains of Actinomycetales. The antibiotic exhibits inhibitory activity against Candida albicans in YNB medium (a synthetic medium), but the activity is significantly reduced in Sabouroud dextrose medium.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
