CBM 301940
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| Category | Enzyme inhibitors |
| Catalog number | BBF-04521 |
| CAS | 902146-11-6 |
| Molecular Weight | 422.32 |
| Molecular Formula | C15H20F6N2O5 |
| Purity | ≥98% |
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Description
Malonyl-CoA decarboxylase (MCD) is found from bacteria to humans, which has important roles in regulating fatty acid metabolism and food intake. CBM 301940 is a potent malonyl-CoA decarboxylase (MCD) inhibitor with IC50 of 23 nM. It suppresses malonyl-CoA degradation and fatty acid oxidation in isolated rat hearts, leading to secondary increase in glucose oxidation.
Specification
| Synonyms | (2S,3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-4-(2-oxoethyl)-2H-pyran-5-carboxylic acid, methyl ester; CBM301940; CBM-301940 |
| Storage | Store at -20°C |
| IUPAC Name | tert-butyl 3-[[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydro-1,2-oxazole-3-carbonyl]amino]butanoate |
| Canonical SMILES | CC(NC(C1=NOC(C(C(F)(F)F)(O)C(F)(F)F)C1)=O)CC(OC(C)(C)(C)=O |
| InChI | InChI=1S/C15H20F6N2O5/c1-7(5-10(24)27-12(2,3)4)22-11(25)8-6-9(28-23-8)13(26,14(16,17)18)15(19,20)21/h7,9,26H,5-6H2,1-4H3,(H,22,25) |
| InChI Key | SBPVPWWNQIKSKL-UHFFFAOYSA-N |
Properties
| Appearance | Off-white Solid |
| Density | 1.4±0.1 g/cm3 |
| Solubility | Soluble in DMSO (100 mM), Ethanol (100 mM) |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
