Get A Quote

Cedarmycin B

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category Antibiotics
Catalog number BBF-00500
CAS 363624-70-8
Molecular Weight 226.27
Molecular Formula C12H18O4

Online Inquiry

Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Streptomyces sp. TP-A0456. It has activities against candida, Cryptococcus neoforme and aspergillus fumigatus. MIC is 12.5-50 ㎍/mL. The anti-bacterial activity is weak.

  • Specification
  • Properties
  • Reference Reading
  • Price Product List
Synonyms (4-Methylene-5-oxo-3-2,3-dihydrofuryl)methyl hexanoate; CTK6D6764; (4-methylene-5-oxo-tetrahydrofuran-3-yl)methyl hexanoate
IUPAC Name (4-methylidene-5-oxooxolan-3-yl)methyl hexanoate
Canonical SMILES CCCCCC(=O)OCC1COC(=O)C1=C
InChI InChI=1S/C12H18O4/c1-3-4-5-6-11(13)15-7-10-8-16-12(14)9(10)2/h10H,2-8H2,1H3
InChI Key ZUGWRISHBCSTOJ-UHFFFAOYSA-N
Appearance Colorless Oily Matter
Antibiotic Activity Spectrum fungi
Solubility Soluble in Chloroform, Methanol
1. Cedarmycins A and B, new antimicrobial antibiotics from Streptomyces sp. TP-A0456
T Sasaki, Y Igarashi, N Saito, T Furumai J Antibiot (Tokyo). 2001 Jul;54(7):567-72. doi: 10.7164/antibiotics.54.567.
Two novel butyrolactone antibiotics, cedarmycins A and B, were isolated from the cultured broth of the actinomycete Streptomyces sp. TP-A0456. The new compounds were purified by HP-20 resin, silica gel, ODS column chromatographies and preparative HPLC, consecutively. The structure of cedarmycin was determined by spectroscopic methods as an alpha,beta-unsaturated butyrolactone with a fatty acid side chain. These compounds showed antibiotic activity against Gram-positive and -negative bacteria and yeasts. Among the tested organisms, cedarmycins potently inhibited the growth of Candida glabrata IFO 0622 with the MIC of 0.4 microg/ml, comparable to that of amphotericin B.

Bio Calculators

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

Recently viewed products

Online Inquiry

Copyright © 2025 BOC Sciences. All rights reserved.

cartIcon
Inquiry Basket