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Cefaclor

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Cefaclor
Category Antibiotics
Catalog number BBF-00706
CAS 53994-73-3
Molecular Weight 367.81
Molecular Formula C15H14ClN3O4S
Purity >98%

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Semisynthetic second generation oral cephalosporin. It is used to treat some infections caused by bacteria such as pneumonia.

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Related CAS 70356-03-5 (hydrate)
Synonyms Cephaclor; Ceclor; Cefaclorum; Kefral; Panoral; Raniclor; 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid
IUPAC Name (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Canonical SMILES C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl
InChI InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1
InChI Key QYIYFLOTGYLRGG-GPCCPHFNSA-N
Appearance Colorless Crystalline Powder
Application Anti-Bacterial Agents
Boiling Point 713.4±60.0 °C (Predicted)
Density 1.357 g/cm3 (Predicted)
Solubility Soluble in Water; Insoluble in Methanol, Benzene, Chloroform
1.Results from the Survey of Antibiotic Resistance (SOAR) 2011-13 in Turkey.
Soyletir G1, Altinkanat G1, Gur D2, Altun B2, Tunger A3, Aydemir S3, Kayacan C4, Aktas Z4, Gunaydin M5, Karadag A5, Gorur H6, Morrissey I7, Torumkuney D8. J Antimicrob Chemother. 2016 May;71 Suppl 1:i71-i83. doi: 10.1093/jac/dkw075.
OBJECTIVES: Data are presented from the Survey of Antibiotic Resistance (SOAR) for respiratory tract infection pathogens collected in 2011-13 from Turkey.
2.A Diagnostic Algorithm for the Detection of Clostridium difficile-Associated Diarrhea.
Yoldaş Ö1, Altındiş M2, Cufalı D3, Aşık G3, Keşli R3. Balkan Med J. 2016 Jan;33(1):80-6. doi: 10.5152/balkanmedj.2015.15159. Epub 2016 Jan 1.
BACKGROUND: Clostridium difficile is a common cause of hospital-acquired diarrhea, which is usually associated with previous antibiotic use. The clinical manifestations of C. difficile infection (CDI) may range from mild diarrhea to fulminant colitis. Clostridium difficile should be considered in diarrhea cases with a history of antibiotic use within the last 8 weeks (community-associated CDI) or with a hospital stay of at least 3 days, regardless of the duration of antibiotic use (hospital-acquired CDI).
3.Results from the Survey of Antibiotic Resistance (SOAR) 2011-13 in the Gulf States.
Jamsheer A1, Rafay AM2, Daoud Z3, Morrissey I4, Torumkuney D5. J Antimicrob Chemother. 2016 May;71 Suppl 1:i45-i61. doi: 10.1093/jac/dkw064.
OBJECTIVES: To provide surveillance data on the susceptibility of community-acquired respiratory tract isolates from four Gulf and Near East countries from 2011 to 2013.
4.Results from the Survey of Antibiotic Resistance (SOAR) 2009-11 in Vietnam.
Van PH1, Binh PT1, Minh NH2, Morrissey I3, Torumkuney D4. J Antimicrob Chemother. 2016 May;71 Suppl 1:i93-i102. doi: 10.1093/jac/dkw069.
OBJECTIVES: To investigate the susceptibility of respiratory tract infection pathogens collected between 2009 and 2011 from the SOAR study in Vietnam.

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