Cefamandole nafate
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Antibiotics |
Catalog number | BBF-00709 |
CAS | 42540-40-9 |
Molecular Weight | 512.49 |
Molecular Formula | C19H17N6NaO6S2 |
Purity | ≥95% |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
It is produced by the strain of Semisynthetic second generation cephalosporin for injection. The activity of gram-positive bacteria was similar to cefthiophene, and it is sensitive to gram-negative bacteria including Escherichia coli, Pneumococci, Proteus, influenzae, typhoid, dysentery and enterobacter, but has no effect on pseudomonas aeruginosa and Serratia. All anaerobic bacteria were sensitive except the fragile bacilli and Clostridium difficile.
- Specification
- Properties
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Synonyms | Cephamandole nafate; Cefamandol nafato; Kefadol; Mandokef; Mandol; O-Formylcefamandole sodium; Sodium O-formylcefamandole; cemandil sodium salt; Cefam; Bergacef; Mandolsan; Sodium (6R,7R)-7-(R)-mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate formate (ester) |
Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
Storage | Store at -20 °C |
IUPAC Name | sodium;(6R,7R)-7-[[(2R)-2-formyloxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
Canonical SMILES | CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(C4=CC=CC=C4)OC=O)SC2)C(=O)[O-].[Na+] |
InChI | 1S/C19H18N6O6S2.Na/c1-24-19(21-22-23-24)33-8-11-7-32-17-12(16(28)25(17)13(11)18(29)30)20-15(27)14(31-9-26)10-5-3-2-4-6-10;/h2-6,9,12,14,17H,7-8H2,1H3,(H,20,27)(H,29,30);/q;+1/p-1/t12-,14-,17-;/m1./s1 |
InChI Key | ICZOIXFFVKYXOM-YCLOEFEOSA-M |
Source | Semi-synthetic |
Appearance | White Acicular Crystal |
Application | Cephalosporin antibiotic |
Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
Melting Point | 190 °C (dec.) |
Solubility | Freely soluble in Water; Sparingly soluble in Methanol; Insoluble in Ether, Chloroform |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
