Cepacin B
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| Category | Antibiotics |
| Catalog number | BBF-00505 |
| CAS | 91682-94-9 |
| Molecular Weight | 286.28 |
| Molecular Formula | C16H14O5 |
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Description
It is produced by the strain of Pseudomonas cepacia SC 11783. It has anti-gram positive and negative bacterial activity.
Specification
| Synonyms | 4,5-Dihydro-5-(2,3:4,5-diepoxy-1-hydroxydodeca-6,7-dien-9,11-diynyl)-2(3H)-furanone; 2(5H)-Furanone, 5-((3'-(1,2-heptadiene-4,6-diynyl)(2,2'-bioxiran)-3-yl)hydroxymethyl)dihydro-; 2(3H)-Furanone, 4,5-dihydro-5-(2,3:4,5-diepoxy-1-hydroxydodeca-6,7-dien-9,11-diynyl)-; CEPACIN-B |
| IUPAC Name | 5-((3'-(hepta-1,2-dien-4,6-diyn-1-yl)-[2,2'-bioxiran]-3-yl)(hydroxy)methyl)dihydrofuran-2(3H)-one |
| Canonical SMILES | C#CC#CC=C=CC1C(O1)C2C(O2)C(C3CCC(=O)O3)O |
| InChI | InChI=1S/C16H14O5/c1-2-3-4-5-6-7-11-14(20-11)16-15(21-16)13(18)10-8-9-12(17)19-10/h1,5,7,10-11,13-16,18H,8-9H2 |
| InChI Key | JMBCDSUOYMQCGL-UHFFFAOYSA-N |
Properties
| Appearance | Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
| Boiling Point | 556.7 °C at 760 mmHg |
| Density | 1.466 g/cm3 |
| Solubility | Insoluble in Water; Soluble in Chloroform, Ethyl Acetate |
Reference Reading
1. Cepacin A and cepacin B, two new antibiotics produced by Pseudomonas cepacia
W L Parker, M L Rathnum, V Seiner, W H Trejo, P A Principe, R B Sykes J Antibiot (Tokyo). 1984 May;37(5):431-40. doi: 10.7164/antibiotics.37.431.
Two new acetylenic antibiotics, cepacins A and B, have been isolated from the fermentation broth of Pseudomonas cepacia SC 11,783 and assigned structures 1 and 2. Cepacin A has good activity against staphylococci (MIC 0.2 micrograms/ml) but weak activity against streptococci (MIC 50 micrograms/ml) and the majority of Gram-negative organisms (MIC values 6.3 approximately greater than 50 micrograms/ml). Cepacin B has excellent activity against staphylococci (MIC less than 0.05 micrograms/ml) and some Gram-negative organisms (MIC values 0.1 approximately greater than 50 micrograms/ml).
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
