Cephalosporin C sodium salt

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Cephalosporin C sodium salt
Category Antibiotics
Catalog number BBF-04162
CAS 51762-04-0
Molecular Weight 437.40
Molecular Formula C16H20N3NaO8S

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BBF-04162 1 g $298 In stock

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Description

Cephalosporin C sodium salt is the salt form of cephalosporin C, which is an antibiotic isolated from fungi of the genus Acremonium.

Specification

Related CAS 61-24-5 (free acid)
Synonyms Sodium cephalosporin C
Storage Store at -20°C
IUPAC Name sodium;(6R,7R)-3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Canonical SMILES CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CCCC(C(=O)O)N)SC1)C(=O)[O-].[Na+]
InChI InChI=1S/C16H21N3O8S.Na/c1-7(20)27-5-8-6-28-14-11(13(22)19(14)12(8)16(25)26)18-10(21)4-2-3-9(17)15(23)24;/h9,11,14H,2-6,17H2,1H3,(H,18,21)(H,23,24)(H,25,26);/q;+1/p-1/t9?,11-,14-;/m1./s1
InChI Key HZWLVUKHUSRPCG-BJIHTTGYSA-M

Properties

Appearance Solid
Antibiotic Activity Spectrum Gram-positive bacteria

Reference Reading

1.Use of alpha-aminoadipic acid for the biosynthesis of penicillin N and cephalosporin C by a Cephalosporium sp.
Warren SC, Newton GG, Abraham EP. Biochem J. 1967 Jun;103(3):891-901.
1. l-alpha-Amino[6-(14)C]adipic acid has been prepared from the dl-amino acid by oxidation of the l-isomer with l-amino acid oxidase to alpha-oxo[6-(14)C]adipic acid and by transamination of the latter with l-glutamic acid in an extract of a Cephalosporium sp. prepared by ultrasonic treatment of the mycelium. 2. The optical configuration of small amounts of (14)C-labelled alpha-aminoadipic acid from the mycelium of the Cephalosporium sp. has been determined by treatment with l-amino acid oxidase and measurement of the proportion of radioactivity subsequently retained on a column of a strong cation-exchange resin. 3. alpha-Aminoadipic acid which had been labelled in the mycelium from [1-(14)C]acetate appeared to contain more than 99% of the l-isomer. 4. l-alpha-Amino[(14)C]adipic acid (sodium salt) was taken up much more rapidly than the d-isomer, or alpha-oxo[6-(14)C]adipic acid, by suspensions of washed mycelium of the Cephalosporium sp.

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