Cinerubin R
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-00643 |
| CAS | 147657-35-0 |
| Molecular Weight | 809.85 |
| Molecular Formula | C42H51NO15 |
Online Inquiry
Description
It is produced by the strain of Streptomyces eurythermuss H17515MY2. Cinerubin R has anti-gram-positive bacteria and inhibition of tumor cell activity, and its inhibition effect on multidrug resistant (MDR) cells is the same as that on protocells.
Specification
| Synonyms | 4''-Aculosyl-4'-rhodinosyl-7-rhodosaminyl-epsilon-pyrromycinone; DTXSID50933177 |
| IUPAC Name | methyl 4-[4-(dimethylamino)-6-methyl-5-[6-methyl-5-[(6-methyl-5-oxo-2H-pyran-2-yl)oxy]oxan-2-yl]oxyoxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate |
| Canonical SMILES | CCC1(CC(C2=C(C3=C(C=C2C1C(=O)OC)C(=O)C4=C(C=CC(=C4C3=O)O)O)O)OC5CC(C(C(O5)C)OC6CCC(C(O6)C)OC7C=CC(=O)C(O7)C)N(C)C)O |
| InChI | InChI=1S/C42H51NO15/c1-8-42(51)17-28(32-21(36(42)41(50)52-7)15-22-33(38(32)48)39(49)35-26(46)10-9-25(45)34(35)37(22)47)57-31-16-23(43(5)6)40(20(4)55-31)58-30-14-12-27(19(3)54-30)56-29-13-11-24(44)18(2)53-29/h9-11,13,15,18-20,23,27-31,36,40,45-46,48,51H,8,12,14,16-17H2,1-7H3 |
| InChI Key | HIMMZWQWBNOPJH-UHFFFAOYSA-N |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria; tumor |
| Melting Point | 158-162 °C |
Reference Reading
1. A new anthracycline antibiotic, cinerubin R. Taxonomy, structural elucidation and biological activity
M Nakata, M Saito, Y Inouye, S Nakamura, Y Hayakawa, H Seto J Antibiot (Tokyo). 1992 Oct;45(10):1599-608. doi: 10.7164/antibiotics.45.1599.
A novel anthracycline antibiotic, cinerubin R, was isolated from the fermentation broth of Streptomyces eurythermus strain H1715MY2. The structure of cinerubin R was elucidated to be 4"-aculosyl-4'-rhodinosyl-7-rhodosaminyl-epsilon-py rromycinone. Cinerubin R was active against Gram-positive bacteria and inhibited the growth of divergent multi-drug-resistant cells to the same extent as their parental cells.
Recommended Products
| BBF-00574 | Bestatin | Inquiry |
| BBF-02577 | Pneumocandin C0 | Inquiry |
| BBF-04621 | Artemisinin | Inquiry |
| BBF-02594 | Pyrrolnitrin | Inquiry |
| BBF-01829 | Deoxynojirimycin | Inquiry |
| BBF-03516 | (±)-Naringenin | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
