Citreamicin γ

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Category Antibiotics
Catalog number BBF-00350
CAS 128999-31-5
Molecular Weight 627.55
Molecular Formula C33H25NO12

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Description

It is produced by the strain of Micromonospora citrea. Citreamicin γ has anti-gram-positive aerobic and anaerobic bacterial activities.

Specification

Synonyms LL E19085 gamma; Citreamicin gamma; 1-((Acetyloxy)methyl)-3a,4-dihydro-16-hydroxy-11,12-dimethoxy-1,3a-dimethyl-(1)benzopyrano(2',3':6,7)naphth(2,1-g)oxazolo(3,2-b)isoquinoline-2,8,14,15,17(1H)-pentone
IUPAC Name (3-hydroxy-23,24-dimethoxy-7,10-dimethyl-5,8,18,27,29-pentaoxo-9,20-dioxa-6 azaheptacyclo[15.12.0.02,14.04,12.06,10.019,28.021,26]nonacosa-1(17),2,4(12),13,15,19(28),21,23,25-nonaen-7-yl)methyl acetate
Canonical SMILES CC(=O)OCC1(C(=O)OC2(N1C(=O)C3=C(C2)C=C4C=CC5=C(C4=C3O)C(=O)C6=C(C5=O)OC7=CC(=C(C=C7C6=O)OC)OC)C)C
InChI InChI=1S/C33H25NO12/c1-13(35)44-12-32(2)31(41)46-33(3)11-15-8-14-6-7-16-23(21(14)27(38)22(15)30(40)34(32)33)28(39)24-25(36)17-9-19(42-4)20(43-5)10-18(17)45-29(24)26(16)37/h6-10,38H,11-12H2,1-5H3
InChI Key KOCXADIQPPHRJW-UHFFFAOYSA-N

Properties

Antibiotic Activity Spectrum Gram-positive bacteria

Reference Reading

1. Citreamicins, novel antibiotics from Micromonospora citrea: isolation, characterization, and structure determination
G T Carter, J A Nietsche, D R Williams, D B Borders J Antibiot (Tokyo). 1990 May;43(5):504-12. doi: 10.7164/antibiotics.43.504.
A new family of antibacterial antibiotics has been isolated from Micromonospora citrea. The compounds, designated citreamicins alpha, beta, gamma, zeta and eta are of the polycyclic xanthone structure type. Their isolation, characterization and structure determination are presented.

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