Clarithromycin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Antibiotics |
Catalog number | BBF-00648 |
CAS | 81103-11-9 |
Molecular Weight | 747.95 |
Molecular Formula | C38H69NO13 |
Purity | >98% |
Online Inquiry
Description
It is produced by the strain of erythromycin. Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, skin and skin structure infections. It prevents bacteria from growing by interfering with their protein synthesis and binds to the subunit 50S of the bacterial ribosome and thus inhibits the translation of peptides. It has similar antimicrobial spectrum as erythromycin, but is more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. It also has bactericidal effect on certain strains, such as Haemophilus influenzae, Streptococcus pneumoniae and Neisseria gonorrhoeae.
Specification
Synonyms | Biaxin; 6-O-Methylerythromycin; Klaricid; Abbott-56268 |
Storage | Store at -20°C |
IUPAC Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione |
Canonical SMILES | CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O |
InChI | InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
InChI Key | AGOYDEPGAOXOCK-KCBOHYOISA-N |
Source | Semi-synthetic |
Properties
Appearance | Colorless Acicular Crystalline |
Application | Anti-bacterial agents |
Antibiotic Activity Spectrum | Gram-negative bacteria |
Boiling Point | 805.5°C at 760 mmHg |
Melting Point | 222-225°C |
Density | 1.18 g/cm3 |
Solubility | Soluble in ethanol, methanol, DMF, DMSO |
Reference Reading
Recommended Products
BBF-03819 | Spinosyn A | Inquiry |
BBF-03908 | Miltefosine | Inquiry |
BBF-03516 | (±)-Naringenin | Inquiry |
BBF-00586 | Brefeldin A | Inquiry |
BBF-02800 | DB-2073 | Inquiry |
BBF-05763 | Cyclosporin C | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2