Clecarmycin A1
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-00368 |
| CAS | |
| Molecular Weight | 548.49 |
| Molecular Formula | C29H24O11 |
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Description
It is produced by the strain of Streptomyces sp. DO-114. Clecarmycin A1 has anti-gram-positive bacteria activity with MIC 0.04-0.33μg/mL and has stronger anti-gram-negative bacteria and candida albicans than C. Clecarmycin A1 also showed strong cytotoxicity, with IC50 of 6.58 mg/mL against HeLa S3 cells, which was 10-20 times stronger than adriamycin.
Specification
| IUPAC Name | 2-hydroxy-5-(5-hydroxy-6-methyl-4-oxooxan-2-yl)-18-methyl-14-[2-methyl-3-(oxiran-2-yl)oxiran-2-yl]-6,13-dioxapentacyclo[9.8.0.03,9.05,7.012,17]nonadeca-1,3(9),10,12(17),14,18-hexaene-4,8,16-trione |
| Canonical SMILES | CC1C(C(=O)CC(O1)C23C(O2)C(=O)C4=C(C3=O)C(=C5C=C(C6=C(C5=C4)OC(=CC6=O)C7(C(O7)C8CO8)C)C)O)O |
| InChI | InChI=1S/C29H24O11/c1-9-4-11-12(24-19(9)14(30)6-17(38-24)28(3)26(39-28)16-8-36-16)5-13-20(22(11)33)25(35)29(27(40-29)23(13)34)18-7-15(31)21(32)10(2)37-18/h4-6,10,16,18,21,26-27,32-33H,7-8H2,1-3H3 |
| InChI Key | ABNJCNGVZLNFJI-UHFFFAOYSA-N |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria; fungi; neoplastics (Tumor) |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
