Colistin sulfate
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Category | Antibiotics |
Catalog number | BBF-04610 |
CAS | 1264-72-8 |
Molecular Weight | Colistin A: 1169.46; Colistin B: 1155.43 |
Molecular Formula | Colistin A: C53H100N16O13; Colistin B: C52H98N16O13 |
Purity | ≥95% |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa.
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- Properties
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Related CAS | 1066-17-7 (free base) |
Synonyms | Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin |
Storage | Store at -20°C |
IUPAC Name | (S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-((R)-1-hydroxyethyl)-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-((R)-1-hydroxyethyl)-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methylheptanamide;sulfate |
Appearance | Crystalline Solid |
Antibiotic Activity Spectrum | Gram-negative bacteria |
Boiling Point | 1536.8°C at 760 mmHg |
Melting Point | 200-220°C |
Solubility | Soluble in Water |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
