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Confluentic acid

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Confluentic acid
Category Others
Catalog number BBF-05477
CAS 6009-12-7
Molecular Weight 500.58
Molecular Formula C28H36O8
Purity ≥95%

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of lichens Lecidea confluens, Pertusaria tuberculifera and P. globularis. It is also isolated from L. tumida, L. macrocarpa and Herpothallon sanguineum.

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Synonyms NSC 249982; Benzoic acid, 2-hydroxy-4-methoxy-6-(2-oxoheptyl)-, 4-carboxy-3-methoxy-5-pentylphenyl ester; 2-Hydroxy-4-methoxy-6-(2-oxoheptyl)benzoic acid 4-carboxy-3-methoxy-5-pentylphenyl ester; 2-Methoxy-4-[2-(2-oxoheptyl)-4-methoxy-6-hydroxybenzoyloxy]-6-pentylbenzoic acid; Confluentinsaeure; Confluentin
Storage Store at -20°C
IUPAC Name 4-[2-hydroxy-4-methoxy-6-(2-oxoheptyl)benzoyl]oxy-2-methoxy-6-pentylbenzoic acid
Canonical SMILES CCCCCC1=C(C(=CC(=C1)OC(=O)C2=C(C=C(C=C2O)OC)CC(=O)CCCCC)OC)C(=O)O
InChI InChI=1S/C28H36O8/c1-5-7-9-11-18-14-22(17-24(35-4)26(18)27(31)32)36-28(33)25-19(13-20(29)12-10-8-6-2)15-21(34-3)16-23(25)30/h14-17,30H,5-13H2,1-4H3,(H,31,32)
InChI Key UANVCGQMNRTKGM-UHFFFAOYSA-N
Appearance Needles
Boiling Point 651.8°C at 760 mmHg
Melting Point 157°C
Density 1.173 g/cm3
Solubility Soluble in Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate
1.Confluentic acid and 2'-O-methylperlatolic acid, monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
Endo Y;Hayashi H;Sato T;Maruno M;Ohta T;Nozoe S Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1198-201.
Monoamine oxidase B (MAO-B) inhibitors were isolated from the bark of a Brazilian plant, Himatanthus sucuuba (SPR.). Assignments of the 1H- and 13C-NMR data using two dimensional (2D)-NMR techniques showed the active components to be known lichen depsides, confluentic acid (1) and 2'-O-methylperlatolic acid (2). The depside (1) showed selective inhibition of MAO-B with IC50 value of 0.22 microM.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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