Cortinarin C

Cortinarin C

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Cortinarin C
Category Antibiotics
Catalog number BBF-01066
CAS 88025-85-8
Molecular Weight 287.31
Molecular Formula C15H17N3O3

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Description

It is produced by the strain of Cortinarius speciosissimus, C. orellanus and C. orellanoides. It is a peptide antibiotic.

Reference Reading

1. Cortinarins in Cortinarius speciosissimus? A critical revision
L Matthies, H Laatsch Experientia. 1991 Jun 15;47(6):634-40. doi: 10.1007/BF01949895.
Fluorescent cyclic decapeptides, the so-called cortinarins, have been claimed to cause the toxicity of the deadly poisonous mushroom Cortinarius speciosissimus. As the structure elucidation described in the literature is doubtful in decisive parts, the proposed structures must be disputed. The present study demonstrates that the fluorescence is mainly due to ergosta-4,6,8(14),22-tetraen-3-one (8) and to photodecomposition products of the nephrotoxin orellanine (1). Moreover, we were not able to reproduce the isolation of fluorescent or any other cyclic peptides related to cortinarins from C. speciosissimus, by various methods.
2. Mushroom toxins of the genus Cortinarius
I R Tebbett, B Caddy Experientia. 1984 May 15;40(5):441-6. doi: 10.1007/BF01952379.
3 major components of the toxic fungus Cortinarius speciosissimus have been isolated and their structures determined as cyclic polypeptides. 2 of these compounds have been shown in laboratory animals to cause nephrotoxicity characteristic of Cortinarius mushroom poisoning.

Bio Calculators

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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