Curvulic acid
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| Category | Antibiotics |
| Catalog number | BBF-01099 |
| CAS | 652-55-1 |
| Molecular Weight | 240.21 |
| Molecular Formula | C11H12O6 |
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Description
It is produced by the strain of Curvularia siddiqui, Penicillum janthynellum C-268. It has weak activity against gram-positive and negative bacteria. Para-aminobenzoic acid can antagonize its action.
Specification
| Synonyms | 2-Acetyl-3,5-dihydroxy-4-methoxy-phenylessigsaeure; 2-Acetyl-3,5-dihydroxy-4-methoxybenzeneacetic acid |
| IUPAC Name | 2-(2-acetyl-3,5-dihydroxy-4-methoxyphenyl)acetic acid |
| Canonical SMILES | CC(=O)C1=C(C(=C(C=C1CC(=O)O)O)OC)O |
| InChI | InChI=1S/C11H12O6/c1-5(12)9-6(4-8(14)15)3-7(13)11(17-2)10(9)16/h3,13,16H,4H2,1-2H3,(H,14,15) |
| InChI Key | QSWOSJNPHIHNIR-UHFFFAOYSA-N |
Properties
| Appearance | Pink Acicular Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
| Melting Point | 154-156 °C |
Reference Reading
1. Penicillium excelsum sp. nov from the Brazil Nut Tree Ecosystem in the Amazon Basin'
Marta Hiromi Taniwaki, John I Pitt, Beatriz T Iamanaka, Fernanda P Massi, Maria Helena P Fungaro, Jens C Frisvad PLoS One. 2015 Dec 30;10(12):e0143189. doi: 10.1371/journal.pone.0143189. eCollection 2015.
A new Penicillium species, P. excelsum, is described here using morphological characters, extrolite and partial sequence data from the ITS, β-tubulin and calmodulin genes. It was isolated repeatedly using samples of nut shells and flowers from the brazil nut tree, Bertolletia excelsa, as well as bees and ants from the tree ecosystem in the Amazon rainforest. The species produces andrastin A, curvulic acid, penicillic acid and xanthoepocin, and has unique partial β-tubulin and calmodulin gene sequences. The holotype of P. excelsum is CCT 7772, while ITAL 7572 and IBT 31516 are cultures derived from the holotype.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
