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Curvulic acid

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Curvulic acid
Category Antibiotics
Catalog number BBF-01099
CAS 652-55-1
Molecular Weight 240.21
Molecular Formula C11H12O6

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Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Curvularia siddiqui, Penicillum janthynellum C-268. It has weak activity against gram-positive and negative bacteria. Para-aminobenzoic acid can antagonize its action.

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Synonyms 2-Acetyl-3,5-dihydroxy-4-methoxy-phenylessigsaeure; 2-Acetyl-3,5-dihydroxy-4-methoxybenzeneacetic acid
IUPAC Name 2-(2-acetyl-3,5-dihydroxy-4-methoxyphenyl)acetic acid
Canonical SMILES CC(=O)C1=C(C(=C(C=C1CC(=O)O)O)OC)O
InChI InChI=1S/C11H12O6/c1-5(12)9-6(4-8(14)15)3-7(13)11(17-2)10(9)16/h3,13,16H,4H2,1-2H3,(H,14,15)
InChI Key QSWOSJNPHIHNIR-UHFFFAOYSA-N
Appearance Pink Acicular Crystal
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria
Melting Point 154-156 °C
1. Penicillium excelsum sp. nov from the Brazil Nut Tree Ecosystem in the Amazon Basin'
Marta Hiromi Taniwaki, John I Pitt, Beatriz T Iamanaka, Fernanda P Massi, Maria Helena P Fungaro, Jens C Frisvad PLoS One. 2015 Dec 30;10(12):e0143189. doi: 10.1371/journal.pone.0143189. eCollection 2015.
A new Penicillium species, P. excelsum, is described here using morphological characters, extrolite and partial sequence data from the ITS, β-tubulin and calmodulin genes. It was isolated repeatedly using samples of nut shells and flowers from the brazil nut tree, Bertolletia excelsa, as well as bees and ants from the tree ecosystem in the Amazon rainforest. The species produces andrastin A, curvulic acid, penicillic acid and xanthoepocin, and has unique partial β-tubulin and calmodulin gene sequences. The holotype of P. excelsum is CCT 7772, while ITAL 7572 and IBT 31516 are cultures derived from the holotype.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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