Cyclo(L-Trp-L-Trp)
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Category | Enzyme inhibitors |
Catalog number | BBF-04359 |
CAS | 20829-55-4 |
Molecular Weight | 372.42 |
Molecular Formula | C22H20N4O2 |
Purity | ≥98% |
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Description
Cyclo(L-Trp-L-Trp) is a cyclic dipeptide with antibacterial activity. It inhibits the growth of 41 out of 49 strains of multidrug resistant A. baumannii as well as B. subtilis, M. luteus, S. aureus, S. cerevisiae, A. niger and C. albicans. It has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines.
Specification
Synonyms | Cyclo(-Trp-Trp) |
Storage | Store at 2-8°C |
IUPAC Name | (3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione |
Canonical SMILES | C1=CC=C2C(=C1)C(=CN2)CC3C(=O)NC(C(=O)N3)CC4=CNC5=CC=CC=C54 |
InChI | InChI=1S/C22H20N4O2/c27-21-19(9-13-11-23-17-7-3-1-5-15(13)17)25-22(28)20(26-21)10-14-12-24-18-8-4-2-6-16(14)18/h1-8,11-12,19-20,23-24H,9-10H2,(H,25,28)(H,26,27)/t19-,20-/m0/s1 |
InChI Key | DNHODRZUCGXYKU-PMACEKPBSA-N |
Properties
Appearance | Light Yellow Powder |
Antibiotic Activity Spectrum | Bacteria |
Boiling Point | 813.4±60.0°C (Predicted) |
Density | 1.364±0.06 g/cm3 (Predicted) |
Solubility | Soluble in Ethanol, DMF, DMSO |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2