Cystothiazole A
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Antibiotics |
Catalog number | BBF-01132 |
CAS | 207399-36-8 |
Molecular Weight | 422.56 |
Molecular Formula | C20H26N2O4S2 |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
It is produced by the strain of Cystobacter fuscus. It has antifungal activity. It can inhibit candida albicans, saccharomyces cerevisiae and aspergillus smoke with MIC of 0.4 μg/mL, 0.1 μg/mL and 1.6 μg/mL, respectively. It also inhibits human tumor cell, such as HPT-116 and K562 cells with MIC of 130 ng/mL and 110 ng/mL, respectively. It has no anti-bacterial effect.
- Specification
- Properties
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Synonyms | Melithiazole E; (+)-cystothiazole A; methyl (2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-[2'-(propan-2-yl)-2,4'-bi-1,3-thiazol-4-yl]hepta-2,6-dienoate; (2E,6E)-(4R,5S)-7-(2'-Isopropyl-[2,4']bithiazolyl-4-yl)-3,5-dimethoxy-4-methyl-hepta-2,6-dienoic acid methyl ester |
IUPAC Name | methyl (2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-[2-(2-propan-2-yl-1,3-thiazol-4-yl)-1,3-thiazol-4-yl]hepta-2,6-dienoate |
Canonical SMILES | CC(C)C1=NC(=CS1)C2=NC(=CS2)C=CC(C(C)C(=CC(=O)OC)OC)OC |
InChI | InChI=1S/C20H26N2O4S2/c1-12(2)19-22-15(11-28-19)20-21-14(10-27-20)7-8-16(24-4)13(3)17(25-5)9-18(23)26-6/h7-13,16H,1-6H3/b8-7+,17-9+/t13-,16+/m1/s1 |
InChI Key | LRTJMINIVSPVMX-ZVJWTWILSA-N |
Appearance | Colorless Acicular Crystal |
Antibiotic Activity Spectrum | Neoplastics (Tumor); Fungi; Yeast |
Melting Point | 111-112 °C |
Solubility | Soluble in Methanol, Chloroform |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
