Cytosporin C

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Category Bioactive by-products
Catalog number BBF-00772
CAS
Molecular Weight 310.38
Molecular Formula C17H26O5

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Description

Cytosporin C is a minor component produced by Cytospora sp.

Specification

IUPAC Name (1aR,2S,4aR,7R,8aS)-2,7-dihydroxy-6,6-dimethyl-3-pentyl-2,4a,7,8-tetrahydro-1aH-oxireno[2,3-e]chromene-4-carbaldehyde
Canonical SMILES CCCCCC1=C(C2C3(CC(C(O2)(C)C)O)C(C1O)O3)C=O
InChI InChI=1S/C17H26O5/c1-4-5-6-7-10-11(9-18)14-17(15(22-17)13(10)20)8-12(19)16(2,3)21-14/h9,12-15,19-20H,4-8H2,1-3H3/t12-,13+,14-,15-,17+/m1/s1
InChI Key HTCLXJMGGBVISX-YCCFLXJFSA-N

Reference Reading

1. Discovery of an angiotensin II binding inhibitor from a Cytospora sp. using semi-automated screening procedures
S Stevens-Miles, M A Goetz, G F Bills, R A Giacobbe, J S Tkacz, R S Chang, M Mojena, I Martin, M T Diez, F Pelaez, O D Hensens, T Jones, R W Burg, Y L Kong, L Huang J Antibiot (Tokyo). 1996 Feb;49(2):119-23. doi: 10.7164/antibiotics.49.119.
Cytosporin A, B and C, three antagonists of [125I]-angiotensin II binding to rat adrenal glands were discovered in fermentations of an endophytic Cytospora sp. during routine screening using semi-automated procedures. The most potent of these displayed an IC50 of 1.5-3 microM and was specific for angiotensin II AT2.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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