Cytovaricin B
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| Category | Enzyme inhibitors |
| Catalog number | BBF-00774 |
| CAS | 129985-88-2 |
| Molecular Weight | 915.15 |
| Molecular Formula | C48H82O16 |
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Description
Cytovaricin B is a Janus kinase-signal transducer and activation protein (JAK-STAT) inhibitor produced by Streptamyces torulosus 3197-GM1.
Specification
| IUPAC Name | (1S,3S,5'S,6S,6'S,8S,9Z,14R,15R,16S,17R,18R,19S,20R,21Z,25S,27R,29R)-14,15,17,19,20-pentahydroxy-6'-[(2R)-2-hydroxybutyl]-16-[(2S,5R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-3-methoxy-5',6,14,18,20,29-hexamethylspiro[4,24,28-trioxatricyclo[23.3.1.03,8]nonacosa-9,21-diene-27,2'-oxane]-23-one |
| Canonical SMILES | CCC(CC1C(CCC2(O1)CC3C(C(O2)CC4(C(CC(CO4)C)C=CCCCC(C(C(C(C(C(C(C=CC(=O)O3)(C)O)O)C)O)OC5CC(C(C(O5)C)O)OC)O)(C)O)OC)C)C)O |
| InChI | InChI=1S/C48H82O16/c1-11-33(49)22-34-28(3)16-20-47(63-34)24-36-29(4)37(64-47)25-48(58-10)32(21-27(2)26-59-48)15-13-12-14-18-45(7,55)44(54)42(62-39-23-35(57-9)41(52)31(6)60-39)40(51)30(5)43(53)46(8,56)19-17-38(50)61-36/h13,15,17,19,27-37,39-44,49,51-56H,11-12,14,16,18,20-26H2,1-10H3/b15-13-,19-17-/t27-,28-,29-,30+,31?,32+,33+,34-,35?,36-,37-,39-,40+,41+,42-,43-,44+,45+,46+,47+,48-/m0/s1 |
| InChI Key | LJKNWVYWRGRCGM-VXJSJQLSSA-N |
Properties
| Appearance | Powder |
| Melting Point | 210-213°C |
| Solubility | Soluble in Methanol, Methyl ether, DMSO, Chloroform, Ethyl acetate |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
