D-Cysteinol

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Category Others
Catalog number BBF-04694
CAS 23517-29-5
Molecular Weight 107.2
Molecular Formula C3H9NOS

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Properties

Boiling Point 261.3±30.0°C (Predicted)
Density 1.144±0.06 g/cm3 (Predicted)

Reference Reading

1. Effect of sparsomycin analogues on the puromycin-peptidyl transferase reaction on ribosomes
C K Lee, R Vince J Med Chem. 1978 Feb;21(2):176-9. doi: 10.1021/jm00200a006.
Sparsomycin analogues in which the unique -S(O)CH2SCH3 moiety was replaced by a variety of more easily accessible side chains were evaluated as inhibitors of the peptidyl transferase reaction with bacterial ribosomes. Competitive inhibition of acetyl[14C]phenylalanylpuromycin formation revealed that the sulfur-containing side chain of sparsomycin could be replaced with hydrophobic moieties, whereas complete removal of the -S(O)CH2SCH3 side chain eliminated the ribosomal binding affinity of sparsomycin. The specificity for the D isomer of S-deoxo-S-propylsparsomycin has established that the chiral carbon of sparsomycin analogues must be identical with the chirality of D-cysteinol for ribosomal binding.

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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