Dactylocycline E

Name: Dactylocycline E
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	Bioactive by-products
Catalog number	BBF-00783
CAS	146064-01-9
Molecular Weight	683.11
Molecular Formula	C31H39ClN2O13

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Dactylocycline is a tetracycline antibiotic produced by Dactylospoangium sp.. Dactylocycline E has anti-Gram-positive bacteria activity.

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Storage

Store at -20°C

Antibiotic Activity Spectrum	Gram-positive bacteria
Boiling Point	832°C at 760 mmHg
Density	1.59 g/cm3
Solubility	Soluble in DMSO

1. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. II. Structure elucidation

A A Tymiak, H A Ax, M S Bolgar, A D Kahle, M A Porubcan, N H Andersen J Antibiot (Tokyo). 1992 Dec;45(12):1899-906. doi: 10.7164/antibiotics.45.1899.

Fermentation of Dactylosporangium sp. (ATCC 53693) produces a mixture of tetracycline derivatives from which several related tetracycline glycosides, the dactylocyclines, were isolated and their structures determined. The most abundant glycoside in initial fermentations was found to be dactylocycline A. Each glycoside proved to be acid sensitive and readily hydrolyzed to a common aglycone, dactylocyclinone. While the aglycone was cross resistant with tetracycline, the dactylocyclines proved active against certain tetracycline-resistant organisms.

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