Darlucin A

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Category Mycotoxins
Catalog number BBF-00786
CAS 162341-15-3
Molecular Weight 320.34
Molecular Formula C19H16N2O3

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Description

Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin A has antibacterial and fungi activity, and weak cytotoxicity.

Properties

Appearance Colorless Oil
Antibiotic Activity Spectrum bacteria; fungi

Reference Reading

1. Darlucins A and B, new isocyanide antibiotics from Sphaerellopsis filum (Darluca filum)
S Zapf, M Hossfeld, H Anke, R Velten, W Steglich J Antibiot (Tokyo). 1995 Jan;48(1):36-41. doi: 10.7164/antibiotics.48.36.
Two new xanthocillin type antibiotics, darlucin A (1) and B (2), were isolated from fermentations of Sphaerellopsis filum (Darluca filum). Their structures were established by spectroscopic methods. The darlucins are the first known compounds with a 1,2-diisocyanoalkene moiety. Both compounds exhibited antibacterial, antifungal and weak cytotoxic activities.

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