Email:
 Phone:
Get A Quote

Demethoxyviridiol

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Demethoxyviridiol
Category Mycotoxins
Catalog number BBF-04223
CAS 56617-66-4
Molecular Weight 324.33
Molecular Formula C19H16O5
Purity >95% by HPLC

Online Inquiry

Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is a mycotoxin produced by the strain of Nodulisporium hinnuleum. It is a fungal metabolite belonging to the wortmannin and viridin classes and an inhibitor of phosphatidylinositol 3-kinase. It affects phospholipid signalling and proliferation of swiss 3T3 cells.

  • Specification
  • Properties
  • Reference Reading
  • Price Product List
Synonyms Desmethoxyviridiol; Cyclopenta(7,8)phenanthro(10,1-bc)furan-6,9-dione, 1,2,3,7,8,11b-hexahydro-1,3-dihydroxy-11b-methyl-, (1R-(1-alpha,3-alpha,11b-alpha))-; (1R,3S,11bR)-1,2,3,7,8,11b-Hexahydro-1,3-dihydroxy-11b-methylcyclopenta[7,8]phenanthro[10,1-bc]furan-6,9-dione; [1R-(1α,3α,11bα)]-1,2,3,7,8,11b-hexahydro-1,3-dihydroxy-11b-methylcyclopenta[7,8]phenanthro[10,1-bc]furan-6,9-dione
Storage Store at -20°C
IUPAC Name (1R,16S,18R)-16,18-dihydroxy-1-methyl-13-oxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),3,5(9),12(19),14-pentaene-6,11-dione
Canonical SMILES CC12C(CC(C3=COC(=C31)C(=O)C4=C2C=CC5=C4CCC5=O)O)O
InChI InChI=1S/C19H16O5/c1-19-11-4-2-8-9(3-5-12(8)20)15(11)17(23)18-16(19)10(7-24-18)13(21)6-14(19)22/h2,4,7,13-14,21-22H,3,5-6H2,1H3/t13-,14+,19-/m0/s1
InChI Key OSSCBUARECIOCW-KSMMKXTCSA-N
Source Nodulisporium sp.
Appearance Crystal
Boiling Point 486.7°C at 760 mmHg
Melting Point 155-157°C
Density 1.534 g/cm3
Solubility Soluble in Ethyl Acetate
1. Viridin-like steroids from Hymenoscyphus pseudoalbidus
Michelle Cleary, Stina Bengtsson, Pierre F Andersson, Jan Stenlid, Anders Broberg Phytochemistry . 2013 Feb;86:195-200. doi: 10.1016/j.phytochem.2012.09.012.
Three furanosteroids were isolated from the ash dieback causing fungus Hymenoscyphus pseudoalbidus along with the known compounds viridiol and demethoxyviridiol. The compounds were characterized by 1D and 2D NMR spectroscopy, LC-HRMS and polarimetry.
2. Hyfraxinic Acid, a Phytotoxic Tetrasubstituted Octanoic Acid, Produced by the Ash ( Fraxinus excelsior L.) Pathogen Hymenoscyphus fraxineus Together with Viridiol and Some of Its Analogues
Marco Masi, Benedetto Teodoro Linaldeddu, Roberta Di Lecce, Antonio Evidente, Lucia Maddau, Lucio Montecchio, Angela Tuzi J Agric Food Chem . 2019 Dec 11;67(49):13617-13623. doi: 10.1021/acs.jafc.9b06055.
A new tetrasubstituted octanoic acid, named hyfraxinic acid (1), was isolated together with known 1-deoxyviridiol (2), viridiol (3), nodulisporiviridin M (4), and demethoxyviridiol (5) from the organic extract ofHymenoscyphus fraxineusresponsible for ash (Fraxinus excelsiorL.) dieback in Europe. Hyfraxinic acid (1) was characterized, using spectroscopic methods, as 2,4-dihydroxy-7-methyl-6-methyleneoctanoic acid. Furthermore, the advanced Mosher method was used to determine the absolute configuration (3R) of 1-deoxyviridiol. Nodulisporiviridin M (4) was isolated for the first time fromH. fraxineus. The phytotoxicity of each compound was tested by a leaf puncture assay onCeltis australisL.,Quercus suberL.,Hedera elixL.,Juglans regiaL., andFraxinus angustifoliaL. leaves. Compounds1,3, and5exhibited remarkable phytotoxicity on all plants tested, inducing necrotic lesions at concentrations of 1.0 and 0.5 mg/mL, while compounds2and4were found to be inactive in this bioassay. These results could contribute to a deeper understanding of the pathogenicity ofH. fraxineus.

Bio Calculators

  • Solution Dilution Calculator
  • Molecular Weight Calculator
  • Molarity Calculator
Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

Calculate
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g

Recently viewed products

Oligomycin A | Rifaximin EP Impurity F | Demethoxyviridiol

Online Inquiry

USA

  • International : 
    US & Canada (Toll free):
  • Fax:
  • Email:

UK

  • Tel:
  • Email:

Copyright © 2025 BOC Sciences. All rights reserved.

cartIcon
Inquiry Basket
Loading ......
Delete selectedGo to checkout