Demethylbleomycin A2 sulfate
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Category | Antibiotics |
Catalog number | BBF-04319 |
CAS | |
Molecular Weight | 1400.51 (free base) |
Molecular Formula | C54H81N17O21S3.xH2SO4 |
Purity | ≥90% |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
A demethylated form of bleomycin A2 which is a major component in standard grade bleomycin. It is formed by heating bleomycin A2. It has high antimicrobial activity against mycobacterium smegmatis compared to bleomycin A2. It has a lower toxicity.
- Specification
- Properties
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Related CAS | 41089-03-6 (free base) |
Synonyms | Bleomycin DM-A2 sulfate; N1-[3-(Methylthio)propyl]bleomycinamide sulfate |
Storage | Store at -20°C under inert atmosphere |
IUPAC Name | [(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-[2-[4-[4-(3-methylsulfanylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate;sulfate |
Appearance | Off-white Solid |
Antibiotic Activity Spectrum | Mycobacteria |
Solubility | Slightly soluble in Acetonitrile, Water |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
