Demethylbleomycin A2 sulfate
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| Category | Antibiotics |
| Catalog number | BBF-04319 |
| CAS | |
| Molecular Weight | 1400.51 (free base) |
| Molecular Formula | C54H81N17O21S3.xH2SO4 |
| Purity | ≥90% |
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Description
A demethylated form of bleomycin A2 which is a major component in standard grade bleomycin. It is formed by heating bleomycin A2. It has high antimicrobial activity against mycobacterium smegmatis compared to bleomycin A2. It has a lower toxicity.
Specification
| Related CAS | 41089-03-6 (free base) |
| Synonyms | Bleomycin DM-A2 sulfate; N1-[3-(Methylthio)propyl]bleomycinamide sulfate |
| Storage | Store at -20°C under inert atmosphere |
| IUPAC Name | [(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-[2-[4-[4-(3-methylsulfanylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate;sulfate |
Properties
| Appearance | Off-white Solid |
| Antibiotic Activity Spectrum | Mycobacteria |
| Solubility | Slightly soluble in Acetonitrile, Water |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
