Deoxyfusarubin
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| Category | Others |
| Catalog number | BBF-01346 |
| CAS | 132899-05-9 |
| Molecular Weight | 290.27 |
| Molecular Formula | C15H14O6 |
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Description
Deoxyfusarubin is produced by the strain of Nectria haematococca.
Specification
| Synonyms | 3,4-dihydro-3,9-dihydroxy-7-methoxy-3-methyl-1H-naphtho(2,3-c)pyran-5,10-dione |
| IUPAC Name | 3,9-dihydroxy-7-methoxy-3-methyl-1,4-dihydrobenzo[g]isochromene-5,10-dione |
| Canonical SMILES | CC1(CC2=C(CO1)C(=O)C3=C(C2=O)C=C(C=C3O)OC)O |
| InChI | InChI=1S/C15H14O6/c1-15(19)5-9-10(6-21-15)14(18)12-8(13(9)17)3-7(20-2)4-11(12)16/h3-4,16,19H,5-6H2,1-2H3 |
| InChI Key | RYQOFJPFFVZQTC-UHFFFAOYSA-N |
Properties
| Boiling Point | 584.6°C at 760 mmHg |
| Density | 1.49 g/cm3 |
Reference Reading
1. 6-O-demethyl-5-deoxyfusarubin and its anhydro derivative produced by a mutant of the fungus Nectria haematococca blocked in fusarubin biosynthesis
D Parisot, M Devys, M Barbier J Antibiot (Tokyo). 1991 Jan;44(1):103-7. doi: 10.7164/antibiotics.44.103.
6-O-Demethyl-5-deoxyfursarubin and 6-O-demethyl-5-deoxyanhydrofusarubin have been isolated from the mutant redD169.yelY9 of the fungus Nectria haematococca blocked in fusarubin biosynthesis. These products were identified on the basis of physico-chemical data by comparison with known substances.
2. A highly diverse spectrum of naphthoquinone derivatives produced by the endophytic fungus Biatriospora sp. CCF 4378
Eva Stodůlková, Petr Man, Marek Kuzma, Jan Černý, Ivana Císařová, Alena Kubátová, Milada Chudíčková, Miroslav Kolařík, Miroslav Flieger Folia Microbiol (Praha). 2015 May;60(3):259-67. doi: 10.1007/s12223-014-0366-7. Epub 2014 Nov 22.
A strain of Biatriospora sp. CCF 4378 was tested for the production of secondary metabolites under submerged fermentation conditions. Eleven compounds were isolated from the culture broth, and the structures of these compounds were determined using HRMS, NMR and X-ray analysis. In addition to six known naphthoquinone derivatives, i.e. ascomycone A, ascomycone B, 6-deoxyfusarubine, 6-deoxyanhydrofusarubine, herbarine and balticol A, one derivative of 2-azaanthraquinone, 6-deoxybostrycoidine, was also identified. Four new natural pyranonaphthoquinones were found, and these natural products were pleorubrin A, pleorubrin B, pleorubrin C and pleorubrin D. The toxicity on human cell lines of the crude naphthoquinone fraction and pure 6-deoxybostrycoidin, ascomycone B, pleorubrin B and 6-deoxyfusarubin was tested. Ascomycone B and 6-deoxyfusarubin elicited rapid cytotoxicity at micromolar concentrations.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
