Dienomycin B
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-01393 |
| CAS | 27542-55-8 |
| Molecular Weight | 285.38 |
| Molecular Formula | C18H23NO2 |
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Description
It is produced by the strain of Streptomyces sp. MC 67-C1. Dienomycin B has weak antibacterial activity.
Specification
| Synonyms | Acetic acid (2R,3S,4S)-3-methyl-2-((1E,3E)-4-phenyl-buta-1,3-dienyl)-piperidin-4-yl ester |
| IUPAC Name | [3-methyl-2-[(1E,3E)-4-phenylbuta-1,3-dienyl]piperidin-4-yl] acetate |
| Canonical SMILES | CC1C(CCNC1C=CC=CC2=CC=CC=C2)OC(=O)C |
| InChI | InChI=1S/C18H23NO2/c1-14-17(19-13-12-18(14)21-15(2)20)11-7-6-10-16-8-4-3-5-9-16/h3-11,14,17-19H,12-13H2,1-2H3/b10-6+,11-7+ |
| InChI Key | SUEACSZSOBUHPC-JMQWPVDRSA-N |
Properties
| Appearance | Colorless Acicular Crystalline |
| Melting Point | 280-281°C |
Reference Reading
1. Structures of trienomycins A, B and C, novel cytocidal ansamycin antibiotics
S Funayama, K Okada, K Iwasaki, K Komiyama, I Umezawa J Antibiot (Tokyo). 1985 Dec;38(12):1677-83. doi: 10.7164/antibiotics.38.1677.
The structures of novel antibiotics, trienomycins A, B and C produced by Streptomyces sp. No. 83-16, have been determined on the basis of their spectroscopical and chemical properties. Trienomycins are unique ansamycin antibiotics with a triene and an 1,3,5-trisubstituted benzene moieties in the molecule. The antibiotics possess potent cytocidal activity against HeLa S3 cells at concentrations of 0.005 (trienomycin A), 0.1 (trienomycin C) and 0.2 micrograms/ml (trienomycin B) (IC50 value), respectively. However, trienomycins showed no antimicrobial activity against the bacteria, fungi and yeasts examined with the exception of weak activity versus Piricularia oryzae at a concentration of 1,000 micrograms/ml.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
