DM1-SMCC
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Mycotoxins |
Catalog number | BBF-04656 |
CAS | 1228105-51-8 |
Molecular Weight | 1072.62 |
Molecular Formula | C51H66ClN5O16S |
Purity | 95% |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-04656 | 10 mg | $298 | In stock |
Online Inquiry
Add to cartCapabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR.
- Specification
- Properties
- Reference Reading
- Price Product List
- QC Data
Synonyms | 2,5-dioxopyrrolidin-1-yl 4-((3-((3-(((2S)-1-(((14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-3-oxopropyl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate; DM1 SMCC; SMCC-DM1 |
Shelf Life | 2 month in rt, long time |
Storage | Store at -20°C |
IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 4-[[3-[3-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-3-oxopropyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]methyl]cyclohexane-1-carboxylate |
Canonical SMILES | CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)ON7C(=O)CCC7=O)C)C)OC)(NC(=O)O2)O |
InChI | InChI=1S/C51H66ClN5O16S/c1-27-10-9-11-37(69-8)51(67)25-35(70-49(66)53-51)28(2)45-50(4,72-45)38(24-42(61)55(6)33-21-31(20-27)22-34(68-7)44(33)52)71-47(64)29(3)54(5)39(58)18-19-74-36-23-43(62)56(46(36)63)26-30-12-14-32(15-13-30)48(65)73-57-40(59)16-17-41(57)60/h9-11,21-22,28-30,32,35-38,45,67H,12-20,23-26H2,1-8H3,(H,53,66)/b11-9+,27-10+/t28-,29+,30?,32?,35+,36?,37-,38+,45+,50+,51+/m1/s1 |
InChI Key | IADUWZMNTKHTIN-MLSWMBHTSA-N |
Appearance | Soild powder |
Application | This active molecular is DM1 with a linker SMCC that can react with antibody to make antibody drug conjugate. |
Antibiotic Activity Spectrum | neoplastics (Tumor) |
Density | 1.4±0.1 g/cm3 |
Solubility | Soluble in DMSO, not in water |
LogP | 3.28 |
BBF-04727 | Strigolactone GR24 | Inquiry |
BBF-05762 | Cyclosporin B | Inquiry |
BBF-03774 | Cephalosporin C Zinc Salt | Inquiry |
BBF-05781 | Emodepside | Inquiry |
BBF-03516 | (±)-Naringenin | Inquiry |
BBF-05728 | Maytansinol | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
