DOB-41
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-02807 |
| CAS | 115666-98-3 |
| Molecular Weight | 370.36 |
| Molecular Formula | C19H18N2O6 |
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Description
DOB-41 is produced by the strain of Pseudomonas DOB-41. It has strong anti-gram-positive bacteria activity, and has the effect of inhibiting tumor. It prolongs the survival of transplanted leukemia P388 mice.
Specification
| Synonyms | Dob-41 antibiotic; Antibiotic dob 41; 6-[(R)-1-[(R)-3-Hydroxy-2-methoxy-1-oxopropoxy]ethyl]-1-phenazinecarboxylic acid |
| IUPAC Name | 6-[(1R)-1-[(2R)-3-hydroxy-2-methoxypropanoyl]oxyethyl]phenazine-1-carboxylic acid |
| Canonical SMILES | CC(C1=C2C(=CC=C1)N=C3C(=N2)C=CC=C3C(=O)O)OC(=O)C(CO)OC |
| InChI | InChI=1S/C19H18N2O6/c1-10(27-19(25)15(9-22)26-2)11-5-3-7-13-16(11)20-14-8-4-6-12(18(23)24)17(14)21-13/h3-8,10,15,22H,9H2,1-2H3,(H,23,24)/t10-,15-/m1/s1 |
| InChI Key | OSEDIRANPWGFRX-MEBBXXQBSA-N |
Properties
| Appearance | Yellow Acicular Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria; neoplastics (Tumor) |
| Boiling Point | 637.7±45.0°C at 760 mmHg |
| Melting Point | 201°C |
| Density | 1.4±0.1 g/cm3 |
Reference Reading
1. Isolation of a new phenazine antibiotic, DOB-41, from Pseudomonas species
J Shoji, R Sakazaki, H Nakai, Y Terui, T Hattori, O Shiratori, E Kondo, T Konishi J Antibiot (Tokyo). 1988 May;41(5):589-94. doi: 10.7164/antibiotics.41.589.
A new phenazine antibiotic, DOB-41, was isolated from the culture broth of a Pseudomonas strain. The antibiotic obtained as yellow crystals showed UV maxima at 255 nm and 370 nm. A molecular formula, C19H18N2O6, was indicated by elemental analysis and mass spectrometry. The structure was elucidated by X-ray diffraction analysis. The antibiotic exhibited inhibitory activity against Gram-positive bacteria, and antitumor effect against leukemia P388 in mice.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
