Drosophilin E
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| Category | Others |
| Catalog number | BBF-01177 |
| CAS | 505-87-3 |
| Molecular Weight | 148.16 |
| Molecular Formula | C9H8O2 |
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Description
It is produced by the strain of Drosophila subatrata.
Specification
| Synonyms | cis-Non-4-en-6,8-diinsaeure |
| IUPAC Name | (Z)-Non-4-ene-6,8-diynoic acid |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Solubility | Soluble in Ethanol |
Reference Reading
1. Evolution and development of male-specific leg brushes in Drosophilidae
Kohtaro Tanaka, Olga Barmina, Ammon Thompson, Jonathan H Massey, Bernard Y Kim, Anton Suvorov, Artyom Kopp Dev Genes Evol. 2022 Dec;232(5-6):89-102. doi: 10.1007/s00427-022-00694-3. Epub 2022 Aug 8.
The origin, diversification, and secondary loss of sexually dimorphic characters are common in animal evolution. In some cases, structurally and functionally similar traits have evolved independently in multiple lineages. Prominent examples of such traits include the male-specific grasping structures that develop on the front legs of many dipteran insects. In this report, we describe the evolution and development of one of these structures, the male-specific "sex brush." The sex brush is composed of densely packed, irregularly arranged modified bristles and is found in several distantly related lineages in the family Drosophilidae. Phylogenetic analysis using 250 genes from over 200 species provides modest support for a single origin of the sex brush followed by many secondary losses; however, independent origins of the sex brush cannot be ruled out completely. We show that sex brushes develop in very similar ways in all brush-bearing lineages. The dense packing of brush hairs is explained by the specification of bristle precursor cells at a near-maximum density permitted by the lateral inhibition mechanism, as well as by the reduced size of the surrounding epithelial cells. In contrast to the female and the ancestral male condition, where bristles are arranged in stereotypical, precisely spaced rows, cell migration does not contribute appreciably to the formation of the sex brush. The complex phylogenetic history of the sex brush can make it a valuable model for investigating coevolution of sex-specific morphology and mating behavior.
2. Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii
Augusto Santos Rampasso, Patrick Michael Ogrady Zootaxa. 2022 Mar 8;5106(1):1-80. doi: 10.11646/zootaxa.5106.1.1.
This checklist contains taxonomic information and distributions for 720 drosophilid species, including all species descended from the most recent common ancestor of the Hawaiian Drosophilidae and all adventive species present in the Hawaiian Islands. The ancestor of the Hawaiian Drosophilidae colonized the archipelago roughly 25 million years ago and now includes 689 described taxa. This includes species placed in the genus Scaptomyza (273 spp), only some of which are Hawaiian endemics (148 spp), and all endemic Hawaiian Drosophila (416 spp). There are also 33 adventive species that have been introduced to Hawaii in the past ~200 years. Taxonomic placement, to the level of species subgroup, and all references related to replacement names and synonyms are included. This is the first comprehensive list to be published in over a decade and includes many recent changes and additions to the fauna, including 130 new species names. This checklist will serve as the basis for future revisionary work on the endemic Hawaiian Drosophilidae, particularly the genus Scaptomyza.
3. Phortica oldenbergi (Diptera: Drosophilidae): A new potential vector of the zoonotic Thelazia callipaeda eyeworm
Marcos Antonio Bezerra-Santos, Ilaria Bernardini, Riccardo Paolo Lia, Jairo Alfonso Mendoza-Roldan, Frederic Beugnet, Marco Pombi, Domenico Otranto Acta Trop. 2022 Sep;233:106565. doi: 10.1016/j.actatropica.2022.106565. Epub 2022 Jun 13.
Thelazia callipaeda is a zoonotic nematode parasitizing the eyes of many hosts species, primarily dogs. To date Phortica variegata and Phortica okadai are the only known vectors of this nematode in Europe and China, respectively. In this study we investigated the role played by a third species, Phortica oldenbergi, as vector of T. callipaeda in Europe. Drosophilid flies of this species were collected in central Italy and maintained in laboratory. One hundred forty P. oldenbergi were experimentally infected with T. callipaeda L1 recovered from field collected gravid females belonging to haplotype 1, which is that detected in several countries in Europe. Seventy-four (i.e., 60 females and 14 males) specimens died at 5 days post infection (d.p.i.) (±1) and scored negative for T. callipaeda larvae at the dissection. Sixty-six (i.e., 46 females and 20 males) P. oldenbergi survived and were dissected at 21 d.p.i. From those, T. callipaeda L3 were detected in the proboscis of two females (3.0%). Overall, at the molecular analysis, 11.4% (n = 16/140; 13 females and 3 males) scored positive for the presence of T. callipaeda DNA. Data herein reported brings further insights on the biology of T. callipaeda by adding P. oldenbergi as a new potential intermediate host under experimental conditions. The role of this drosophilid in the transmission cycle of T. callipaeda needs to be confirmed under natural conditions.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
