Elizabethin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-01203 |
| CAS | 78361-81-6 |
| Molecular Weight | 670.83 |
| Molecular Formula | C35H58O12 |
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Description
It is produced by the strain of Streptomyces elizabethii. It has antifungal activity.
Specification
| IUPAC Name | (17Z,19E,21E,23E,25E)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one |
| Canonical SMILES | CCCCCC(C1C(CC(CC(CC(CC(CC(C(C(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O)O |
| InChI | InChI=1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14- |
| InChI Key | AGJUUQSLGVCRQA-UIIFIEQTSA-N |
Properties
| Appearance | Light Yellow Crystal |
| Antibiotic Activity Spectrum | Fungi |
| Boiling Point | 914.0 °C at 760 mmHg |
| Melting Point | 225-227 °C |
| Density | 1.196 g/cm3 |
| Solubility | Soluble in Methanol, DMF |
Reference Reading
1. The Beginnings of English Paracelsian Lexicography: Two Collections of Words from Elizabethan Cambridge
John Considine Ambix. 2022 May;69(2):163-189. doi: 10.1080/00026980.2021.2012315. Epub 2022 Mar 16.
This article identifies the first two collections of Paracelsian words to have been printed in England: a body of 153 new and rare words, or new senses of existing words, dispersed in the third edition of Thomas Thomas's Latin-English Dictionarium of 1592, and a list of forty-three words forming part of Joseph Hall's Latin prose satire Mundus alter et idem, published in 1605. The Paracelsian material in the Dictionarium has been practically unknown until now, and the Paracelsian material in Mundus alter et idem has been insufficiently studied. Both collections of words are edited here, with discussion of their sources and the principles on which they were selected, and with discussion of their influence for the period of more than half a century when they were the only collections of Paracelsian words printed in England.
2. "The Cone of Shame": Welfare Implications of Elizabethan Collar Use on Dogs and Cats as Reported by their Owners
Yustina Shenoda, Michael P Ward, Dorothy McKeegan, Anne Fawcett Animals (Basel). 2020 Feb 20;10(2):333. doi: 10.3390/ani10020333.
Elizabethan collars are used in companion animals primarily to prevent self-trauma and associated negative welfare states in animals. However, they have been anecdotally associated with negative impacts on animal health and welfare including distress, abraded/ulcerated skin and misadventure. This study aimed to characterise the welfare impacts of Elizabethan collar use on companion dogs and cats, as reported by owners. Owners of pets who wore an Elizabethan collar during the past 12 months were surveyed about the impacts that the use of Elizabethan collars had on animal activities, in particular sleep, eating, drinking, exercise, interactions with other animals, as well as overall quality of life (QOL). The majority of 434 respondents (77.4%) reported a worse QOL score when their companion animal was wearing the collar, significantly so when the Elizabethan collar irritated their pet or impacted on their ability to drink or play. While other factors are likely to impact animal welfare during veterinary treatment that necessitates the use of Elizabethan collars, this study suggests that Elizabethan collars themselves might have negative welfare impacts in a range of domains including nutrition, environment, health, behaviour and mental state. We recommend that animal owners are informed about potential negative impacts of Elizabethan collars and harm minimisation strategies. Where possible, alternative methods of preventing self-trauma should be explored.
3. Corneal Emergencies
Ellen B Belknap Top Companion Anim Med. 2015 Sep;30(3):74-80. doi: 10.1053/j.tcam.2015.07.006. Epub 2015 Jul 9.
Corneal emergencies can be due to a number of different causes and may be vision threatening if left untreated. In an attempt to stabilize the cornea, it is of benefit to place an Elizabethan collar on the patient to prevent further corneal damage. This article discusses the diagnosis, prognosis, and management of corneal emergencies in dogs and cats.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
