Endophenazine D
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| Category | Antibiotics |
| Catalog number | BBF-01230 |
| CAS | |
| Molecular Weight | 284.27 |
| Molecular Formula | C15H12N2O4 |
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Description
It is produced by the strain of Streptomyces anulatus. It has activity against gram-positive bacteria and filamentous fungi such as mucor and Penicillium. It has herbicidal activity against Lemna minor.
Specification
| IUPAC Name | 2-(5,10-dihydrophenazine-1-carbonyloxy)acetic acid |
| Canonical SMILES | C1=CC=C2C(=C1)NC3=CC=CC(=C3N2)C(=O)OCC(=O)O |
| InChI | InChI=1S/C15H12N2O4/c18-13(19)8-21-15(20)9-4-3-7-12-14(9)17-11-6-2-1-5-10(11)16-12/h1-7,16-17H,8H2,(H,18,19) |
| InChI Key | KFXYGNFKEYTDSF-UHFFFAOYSA-N |
Properties
| Appearance | Colorless Solid |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Fungi |
| Solubility | Soluble in Methanol |
Reference Reading
1. Endophenazines A-D, new phenazine antibiotics from the arthropod associated endosymbiont Streptomyces anulatus. I. Taxonomy, fermentation, isolation and biological activities
Klaus Gebhardt, Judith Schimana, Philipp Krastel, Konrad Dettner, Joachim Rheinheimer, Axel Zeeck, Hans-Peter Fiedler J Antibiot (Tokyo). 2002 Sep;55(9):794-800. doi: 10.7164/antibiotics.55.794.
Four new members of the phenazine family, endophenazines A-D, and the already known phenazine-1-carboxylic acid (tubermycin B) were detected in the culture broth of various endosymbiotic Streptomyces anulatus strains by chemical screening in a combination of TLC-staining reagents and HPLC-diode array analysis. The endosymbiotic strains were isolated from four different arthropod hosts at various sites. The new phenazine compounds showed antimicrobial activities against Gram-positive bacteria and some filamentous fungi, and herbicidal activity against Lemna minor (duckweed).
2. Endophenazines A-D, new phenazine antibiotics from the athropod associated endosymbiont Streptomyces anulatus II. Structure elucidation
Philipp Krastel, Axel Zeeck, Klaus Gebhardt, Hans-Peter Fiedler, Joachim Rheinheimer J Antibiot (Tokyo). 2002 Sep;55(9):801-6. doi: 10.7164/antibiotics.55.801.
A detailed screening of the secondary metabolite pattern produced by different athropod associated strains of the species Streptomyces anulatus resulted in the isolation and structure elucidation of the endophenazines A-D (2, 4-6). The structures were assigned by spectroscopic methods and chemical transformations. 4 represents a chromophoric system based on a phenazin-7-one, 5 and 6 are new 5,10-dihydrophenazine derivatives.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
