Epihygromycin

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Category Antibiotics
Catalog number BBF-00842
CAS 75081-92-4
Molecular Weight 511.47
Molecular Formula C23H29NO12

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Description

Epihygromycin is a glycoside antibiotic produced by Streptomyces noboritoensis KCC-S-0065. It has weak activity against Gram-positive bacteria.

Properties

Antibiotic Activity Spectrum Gram-positive bacteria
Melting Point 114-117°C

Reference Reading

1. Hygromycin and epihygromycin from a bacterium, Corynebacterium equi No. 2841
Y Wakisaka, K Koizumi, Y Nishimoto, M Kobayashi, N Tsuji J Antibiot (Tokyo). 1980 Jul;33(7):695-704. doi: 10.7164/antibiotics.33.695.
A newly isolated bacterium which produces antibacterial substances as below was taxonomically characterized and identified with Corynebacterium equi. The major antibiotic produced was determined to be hygromycin by direct comparison. The minor component, newly named epihygromycin was proved to be an epimer of hygromycin by spectrosocopic evidences and by chemical conversions. The presence of epihygromycin in the metabolites of Streptomyces noboritoensis (reported to be a hygromycin producer) was also observed.

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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