Ertapenem Sodium
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Category | Antibiotics |
Catalog number | BBF-03993 |
CAS | 153773-82-1 |
Molecular Weight | 497.50 |
Molecular Formula | C22H24N3NaO7S |
Purity | 95% by HPLC |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-03993 | 1 g | $439 | In stock | |
BBF-03993 | 5 g | $999 | In stock |
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Product Description
Ertapenem Sodium is the sodium salt of ertapenem. Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections.
- Specification
- Properties
- Reference Reading
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- QC Data
Related CAS | 153832-38-3 (disodium) 153832-46-3 (free acid) |
Synonyms | Invanz; Ertapenem sodium salt; MK-0826 |
Storage | Store at -20°C |
IUPAC Name | sodium;3-[[(2S,4S)-4-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]sulfanyl]pyrrolidine-2-carbonyl]amino]benzoate |
Canonical SMILES | CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)NC4=CC=CC(=C4)C(=O)[O-])C(=O)O)C(C)O.[Na+] |
InChI | InChI=1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1 |
InChI Key | ZXNAQFZBWUNWJM-HRXMHBOMSA-M |
Appearance | White to Light Yellow Solid |
Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
Boiling Point | 813.9°C at 760 mmHg |
Solubility | Soluble in DMSO |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
