Eurocidin E
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-00882 |
| CAS | 130433-02-2 |
| Molecular Weight | 779.91 |
| Molecular Formula | C40H61NO14 |
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Description
Eurocidin E is a pentaene macrolide antibiotic produced by Streptoverticillium eurocidicum IFO 13491. It has anti-yeast, rice pear stalk, streptomyces, trichophyton and trichomonas activity.
Specification
| IUPAC Name | (17Z,21Z)-25-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-13-butan-2-yl-1,3,9,29-tetrahydroxy-7,11-dioxo-12,31-dioxabicyclo[25.3.1]hentriaconta-15,17,19,21,23-pentaene-28-carboxylic acid |
| Canonical SMILES | CCC(C)C1CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CCCC(=O)CC(CC(=O)O1)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O |
| InChI | InChI=1S/C40H61NO14/c1-4-24(2)31-18-13-11-9-7-5-6-8-10-12-17-29(53-39-37(48)35(41)36(47)25(3)52-39)21-32-34(38(49)50)30(45)23-40(51,55-32)22-27(43)16-14-15-26(42)19-28(44)20-33(46)54-31/h5-13,17,24-25,27-32,34-37,39,43-45,47-48,51H,4,14-16,18-23,41H2,1-3H3,(H,49,50)/b6-5?,9-7-,10-8-,13-11?,17-12?/t24?,25-,27?,28?,29?,30?,31?,32?,34?,35+,36-,37+,39+,40?/m1/s1 |
| InChI Key | QHYNZYOPJOICJB-VNUXKHFZSA-N |
Properties
| Appearance | Light Yellow Flake Crystal |
| Antibiotic Activity Spectrum | fungi; yeast; parasites |
| Melting Point | 138-139°C(dec.) |
Reference Reading
1. Studies on inhibitors of rat mast cell degranulation produced by microorganisms. I. Screening of microorganisms, and isolation and physico-chemical properties of eurocidins C, D and E
K Nakagomi, M Takeuchi, H Tanaka, N Tomizuka, T Nakajima J Antibiot (Tokyo). 1990 May;43(5):462-9. doi: 10.7164/antibiotics.43.462.
Microorganisms producing anti-inflammatory substances were screened by the inhibitory effect on mast cell degranulation. Three new compounds related to pentaene macrolide eurocidins, eurocidins C, D and E, have been isolated from the culture broth of Streptoverticillium eurocidicum IFO 13491 as the inhibitors. Their molecular weights and molecular formulae were estimated as 781.89 and C39H59NO15 for eurocidin C, 795.92 and C40H61NO15 for eurocidin D, and 779.92 and C40H61NO14 for eurocidin E, respectively.
2. Studies on inhibitors of rat mast cell degranulation produced by microorganisms. II. Structure elucidation of eurocidins D and E
K Nakagomi, S Sakai, H Tanaka, N Tomizuka, Y Kawakami, T Nakajima J Antibiot (Tokyo). 1990 May;43(5):470-6. doi: 10.7164/antibiotics.43.470.
The planar structures of new eurocidin related compounds, eurocidins D and E, were elucidated from 1H-1H shift correlated 2D NMR spectra and other NMR data. All protons in the molecules were assigned. Eurocidins D and E have novel pentaenic structures of eurocidin family.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
